Conditions Of Vulva And Vagina - Moulton Flashcards
What contains a cheesy material and causes a mass on inner surface of labia minora/majora?
Sebaceous cyst
What FIGO stage is carcinoma has extended beyond the true pelvis or mucosa of the bladder/rectum?
IV
Psoriasis inheritance?
Vulva appears how?
AD
Velvety
SCC of vagina presents how?
Physical exam?
Dx?
Abnormal vaginal discharge/bleeding
Hematuria
Ulcerative, exophyitc growth
Punch biopsy
What is described by extremely tender lesions w/severe introital dyspareunia and occasional vulvar pain?
Vulvar vestibulitis
What involves ulcerations in the genital, oral areas w/uveitis?
Bechet’s syndrome
What presents as a pruritic, raised, ulcerated, warty appearing lesion on labia majora?
SCC of vulva
What is an autoimmune blistering disease involving the vulvovaginal and conjunctival areas?
Pemphigus
What creates a double vagina?and may create a blind vaginal pouch?
Middle longitudinal septum
Most common vulvar tumor?
Mean age?
SCC
65
Normal pH of vagina?
What thrives there?
3.8-4.2
Lactic acid, H2O2, lactobacilli
What VIN has cofactors of vulvar atypia?
Low association w/cervical neoplasia?
Both Type 2 (Differentiated)
What has cauliflower-like lesions and is a condition in which radiation is contraindicated bc it may induce anaplastic transformation?
Verrucous carcinoma
Eccrine gland tumor?
Syringoma
What is common after a bike injury, birth trauma or sexual assault?
Vulvar hematoma
VIN usual type is associated with what?
HPV16
Smoking
Immunocompromised
Differentiated VIN associated w/what?
Not HPV or smoking
Lichen sclerosis
What is located in the posterior/lateral wall in the lower third of the vagina and is freq assoc w/gynecological surgery or lacerations from childbirth?
Inclusion cyst
What is the 2nd most common vulvar cancer?
Survival rate?
Malignant melanoma
30%
What is a severe pruritic raised yellow retention cyst in the axilla and labia major/minora resulting from keratin-plugged inflammation of apocrine glands?
Fox-Fordyce disease
On exam, what shows purplish, polygonal papules that may appear in an erosive form and causes burning and severe insertional dyspareunia?
Lichen planus
What FIGO stage is carcinoma has spread to the bladder/rectum?
IVa
Most common cause of vaginitis is what?
Due to what?
Bacterial vaginosis
G. Vaginalis
What FIGO stage is carcinoma has involved the subvaginal tissue but not extended onto the pelvic side wall?
II
Prognosis of malignant melanoma?
Poor
What results from blockage and accumulation of purulent material and is a very painful inflammatory mass?
Bartholin gland abscess
VIN III known as what?
Linked to what?
SCC in situ
Vulvar cancer
What VIN has a strong association w/condylomata and STD?
Type I usual
What laundry list can alter microflora of vagina?
Abs
Douching
Sex
Foreign body
After menopause, what happens to the pH of the vagina?
Causes what?
rises
Bacterial vaginosis
What has a hyaline zone in the superficial dermis?
Acanthosis w/elongation of rete ridges?
Lichen sclerosis
Lichen simplex chronicus (squamous cell hyperplasia)
Most common symptom of VIN?
Have what appearance?
Pruritus
20% - warty appearance
What is the most common type of genital cyst?
Features?
Epidermal Inclusion cyst
Mobile, nontender, slow growing
What arises from Von Recklinghausen’s disease?
Neurofibroma
What causes androgen insensitivity disorder?
Karyotype?
Inheritance?
Androgen receptor defect
46 XY
X-linked recessive
What is the most common vulvovaginal tumor and usually causes unilateral swelling?
Women over 40 may get what?
Bartholin’s cyst
Bartholin carcinoma
What causes labial agglutination?
How is labial agglutination treated?
Lack of estrogen
Estrogen cream and massage
Androgen insensitivity syndrome has what clinical features?
Undescended testes
Absent uterus/fallopian tubes
Ambiguous genitalia
What is the most common b9 solid tumor of the vulva?
Fibroma
Sequelae of lichen sclerosis?
Loss of labia minora/majora
Clit can become inverted and trapped
Key hole?
Lichen sclerosis
What appears as a benign, small, fleshy red outgrowth at the distal edge of the urethra?
Urethral caruncles
What rare lesion arises from sweat gland of the vulva?
Hidradenoma
What causes intense pruritis, dyspareunia, and burning pain and is most frequently found on the vulva of menopausal women?
Tx?
Lichen sclerosis
Clobetasol
What appears as multiple 2-3 mm red lesions usually in 4th and 5th decade?
Angioma
Biopsy with hyperkeratosis of the keratin layer and elongated rete ridges indicates what?
Lichen simplex chronicus
Squamous cell hyperplasia
