Normal and abnormal growth Flashcards

1
Q

why do mothers with diabetes have larger babies

A

insulin acts as a growth factor

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2
Q

what is the Z score

A

number of standard deviations away from the mean that a person has from the mean

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3
Q

is a normal distribution of 100 people, how many fall within z score 1SD of the mean?

A

66%

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4
Q

is a normal distribution of 100 people, how many fall within z score 2SD of the mean?

A

95%

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5
Q

measurement of head circumference?

A

take it 3 times and take an average from the widest part of the head

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6
Q

why are overweight children more likely to enter puberty sooner

A

higher leptin, which stimualtes GnRH production

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7
Q

what volume testicle has entered puberty

A

4ml

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8
Q

at what age would puberty be regarded as delayed?

A

13 in girls

14 in boys

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9
Q

when does height velocity peak in girls and boys

A

12 in girls

14 in boys

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10
Q

calculating parental height and normal values?

A

mid parental height is a chart to cross over parental height to calculate centile
anything within 2SD is normal

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11
Q

investigation of growth problem?

A
Hx and exam 
parental heights 
bloods - IGF1, testosterone, thyroid, oestradiol, gonadotrophins
bone age 
MRI brain 
USS uterus
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12
Q

dysmorphic disorders leading to short stature

A

down syndrome
turner syndrome
achondroplasia
prader-wili

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13
Q

cause of short stature

A
genetic 
bone age 
dysmorphic disroders 
endocrine disorders
deprivation 
chronic disease
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