Normal and abnormal growth Flashcards
why do mothers with diabetes have larger babies
insulin acts as a growth factor
what is the Z score
number of standard deviations away from the mean that a person has from the mean
is a normal distribution of 100 people, how many fall within z score 1SD of the mean?
66%
is a normal distribution of 100 people, how many fall within z score 2SD of the mean?
95%
measurement of head circumference?
take it 3 times and take an average from the widest part of the head
why are overweight children more likely to enter puberty sooner
higher leptin, which stimualtes GnRH production
what volume testicle has entered puberty
4ml
at what age would puberty be regarded as delayed?
13 in girls
14 in boys
when does height velocity peak in girls and boys
12 in girls
14 in boys
calculating parental height and normal values?
mid parental height is a chart to cross over parental height to calculate centile
anything within 2SD is normal
investigation of growth problem?
Hx and exam parental heights bloods - IGF1, testosterone, thyroid, oestradiol, gonadotrophins bone age MRI brain USS uterus
dysmorphic disorders leading to short stature
down syndrome
turner syndrome
achondroplasia
prader-wili
cause of short stature
genetic bone age dysmorphic disroders endocrine disorders deprivation chronic disease