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PHARM 203 > Noradrenergic Drugs > Flashcards

Noradrenergic Drugs Flashcards

1
Q

Noradrenaline (Transmission)

A

Transmitter, sympathetic

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2
Q

Adrenaline (Transmission)

A

Hormone, adrenal medulla

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3
Q

Noradrenaline Agonist Action

A

alpha: Increase Heart Rate
beta: Bronchodilation

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4
Q

Adrenaline Agonist Action

A

alpha: Increase Heart Rate
beta: Bronchodilation

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5
Q

Dopamine

A

Transmitter, CNS
Precursor to NA and A

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6
Q

Isoprenaline

A

Synthetic derivative of NA

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7
Q

Phenylephrine

A

Alpha 1 Agonist

Treats Nasal Decongestion (Vasoconstriction)

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8
Q

Salbutamol

A

Beta 2 Agonist

Treats Asthma (Bronchodilation)
Delays Premature Labour (Relaxes Uterus)

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9
Q

Salmeterol

A

Beta 2 Agonist

Treats Asthma (Bronchodilation)

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10
Q

Mirabegron

A

Beta 3 Agonist

Treats Overactive Bladder (Relaxes Bladder)

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11
Q

Phenoxybenzamine

A

Non-Selective Alpha Antagonist

Decreases Stress Hormones

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12
Q

Prazosin

A

Alpha 1 Antagonist

Treats Hypertension (Inhibits Vasoconstriction)

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13
Q

Doxazosin

A

Alpha 1 Antagonist

Treats Hypertension (Inhibits Vasoconstriction)

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14
Q

Propranolol

A

Non-Selective Beta Partial Antagonist

Beta 1: Decreases BP and Cardiac Output
(Treats Hypertension, Angina)
Beta 2: Treats Tremors

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15
Q

Alprenolol

A

Non-Selective Beta Partial Antagonist

Beta 1: Decreases BP and Cardiac Output
(Treats Hypertension, Angina)
Beta 2: Treats Tremors

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16
Q

Metoprolol

A

Beta 1 Antagonist

Decreases BP and Cardiac Output

17
Q

Atenolol

A

Beta 1 Antagonist

Decreases BP and Cardiac Output

18
Q

Nebivolol

A

Beta 1 Antagonist
Increases NO (Causes Vasodilation)

Decreases BP and Cardiac Output

19
Q

Labetalol

A

Alpha/Beta antagonist

Treats Hypertension in pregnancy (Lowers BP)

20
Q

Carvedilol

A

Alpha1/Beta antagonist

Treats Heart Failure

21
Q

a-methyl-tyrosine

A

Inhibits tyrosine hydroxylase
Inhibits NA and Adrenaline synthesis

Prevents adrenal gland tumour overactivation

22
Q

Methyldopa

A

Builds up and displaces NA in synaptic vesicles
Less active than NA on alpha 1 receptors

Not broken down by MAO

23
Q

L-DOPS

A

Prodrug
Converted into NA

24
Q

Amphetamine

A

Stimulates NA release
Inhibits NA reuptake

Increases NA concentration in synapse

25
Q

Ephedrine

A

Stimulates NA release
Beta Agonist

Increase NA concentration in synapse

26
Q

Imipramine

A

Blocks NET, inhibits NA reuptake
Anti-cholingergic effects

27
Q

Cocaine

A

Blocks NET, inhibits NA reuptake

28
Q
A

PHARM 203 (19 decks)

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