Nonbezodiazepine Hypnotics Flashcards
1
Q
Name the 3 drugs belonging to this class.
A
Zolpidem
Zaleplon
Eszopiclone
2
Q
Clinical use of nonBZD hypnotics?
A
- sleep disorders, esp when sleep onset is delayed
3
Q
Mechanism of action of nonBZD hypnotics.
A
They bind to GABA-A receptor sites (close to BZD site)
-facilitate chloride channel opening
4
Q
What other NBZD drugs can be used in sleep disorders? (Also with little side effects)
A
Melatonin Receptor Agonists
Ramelteon, Tasimelteon
activate MT1 and MT2 receptors in suprachiasmatic nucleus