Non opioid pain and inflammation

Question 1

Common NSAIDS

Answer 1

• Ibuprofen (advil, motrin)
• naproxen (aleve, naprosyn)

BBW- CV and GI risk

Question 2

Meloxicam (mobic, vivlodex)

Answer 2

• NSAID- more COX-2 specific
• used for OA, RA, JRA
• BBW- CV and GI risk
• Containdication- hypersensitivity
• side effects and cautions- CV, HTN, GI, renal, some elevation hepatic enzymes in some patients, asthma, nausea, diarrhea, abdominal pain

Question 3

Diclofenac Gel

Answer 3

• Voltaren

- recommended over oral NSAIDs in adults over age 65

Question 4

duloxetine hydrochloride (cymbaltal, Irenka)

Answer 4

• SNRI
• indications- chronic msk pain, diabetic neuropathy pain, fibromyalgia, GAD, MDD
  BBW- suicidal thoughts and behaviors
  MOA- inhibits reuptake of serotonin and nEPI
  Contraindications- use of MAOIs within 14 days, use with linezolid or IV methylene blue
  Side effects- drowsiness, headache, dizziness, diarrhea, xerostomia