Non-opioid Intravenous Agents Flashcards
1
Q
Ketamine - Dose/Timing
A
- 1 – 2 mg/kg
- onset: 30 seconds
- duration: 5 – 10 minutes
2
Q
Ketamine - Indications
A
- used for induction, maintenance and conscious sedation
- bronchodilating effect – good in asthmatics
- profound analgesia
3
Q
Ketamine - Adverse effects
A
- hallucinations, anxiety with early stimulation of patient post-op
- ↑ ICP and intraocular pressure
- ↑ oral secretions
- hypertension
4
Q
Ketamine - Comments
A
- maintain quiet environment while patient recovering
- successful use in children with minimal side effects
- related to PCP and LSD (“special K”)
- 3rd line option after opioid and non-opioid analgesics have failed
- “Date Rape” drug
5
Q
Propofol - Dose/Timing
A
- 1.5 – 3 mg/kg (induction)
- 5 – 50 µg/k g/min (maintenance)
- onset: < 40 seconds
- peak: 1 – 3 minutes
- duration: 3 – 10 minutes
6
Q
Propofol - Indications
A
- Short-acting IV hypnotic/amnesic agent
- used for induction, maintenance, conscious sedation
- ongoing management of ventilated patients
- rapidly metabolized without accumulation
7
Q
Propofol - Adverse Effects
A
- Hypotension
- Painful upon injection
- Lowers inhibitions
- Potenti respiratory depressant
8
Q
Propofol - Comments
A
- Rapid emergence
- Antiemetic properties
- Reduce dose in elderly
- Not recommended in children <3 yrs
- Avoid in pts with egg allergy
- Strict aseptic technique with infusion
- Plastic is degraded b drug therefore do not use 3 way stopcocks/change tubing q 24 hrs
9
Q
Thiopental - Dose/Timing
A
- 4-6 mg/kg
- Onset: 30-60 seconds
- Duration: 5-10 minutes
10
Q
Thiopental - Indications
A
- Short-acting barbituate general anesthetic
- 1st degree use with ECTs
- Used to stop seizures in an emergency situation
11
Q
Thiopental - Adverse Effects
A
- Hypotension
- Possible laryngospasm, bronchospasm on induction
- Pain at injection site
12
Q
Thiopental - Comments
A
• Anti-analgesic effect - may decrease patient’s pain threshold
