non-melanoma skin cancer

Question 1

red, crusted bump, growing, occasional itch, dry and rough, bleeds with trauma

Answer 1

squamous cell carcinoma

biopsy and surgically remove

Question 2

Most common skin cancer in people with white/fair skin is

Answer 2

squamous cell carcinoma

Question 3

which cancer has a higher mortality, SCC or BCC

Answer 3

SCC - higher rate of mets

Question 4

cell of origin for SCC

Answer 4

keratinocytes

Question 5

SCC is due to

Answer 5

CUMULATIVE UV exposure

Question 6

SCC in non-exposed areas is likely due to

Answer 6

chemical carcinogen - arsenic

Question 7

friable lesion
indurated
asymptomatic
may be pruritic

Answer 7

SCC

Question 8

circumscribed pink-red patch or thin plaque, with scaly or rough surface - does NOT invade the dermis is

Answer 8

SCC in situ - bowen’s disease

Question 9

rough red-pink papules, scaly

scattered on forehead and temple

Answer 9

actinic keratosis

Question 10

pre-malignant lesion arising from a keratinocyte is

Answer 10

actinic keratosis

Question 11

p53 tumor suppressor mutation, xeroderma pigmentosum or albinism are risk factors for

Answer 11

actinic keratosis

Question 12

Actinic keratosis is often seen

Answer 12

on a background of damaged skin

Question 13

crateriform, erythematous nodule, central keratinous core, with volcano appearnce

Answer 13

keratocanthoma

- biopsy - r/o SCC

Question 14

extensive sun exposure

pearly pink papule with telangectasias

Answer 14

BCC

Question 15

Rolled pearly borders are highly suggestive of

Answer 15

BCC

Question 16

what is the next step after identifying what looks like a BCC

Answer 16

ALWAYS BIOPSY FIRST

Question 17

pigmented or skin colored nevus
doesnt grow, doesnt bleed or scab
no rolled border or ulceration
appearing early in life

Answer 17

Intradermal nevus

Question 18

telangiectatic, yellowish/pink lesion with a central dimple with other nearby lesions

Answer 18

Sebaceous hyperplasia

Question 19

Fibrous papule, flesh-colored tolight red, firm

often solitary, frequently on the nose

Answer 19

Angiofibroma

Question 20

ROUGH irregular surface, not smooth
STUCK-ON appearance
dull
no telangiectasias

Answer 20

Seborrheic keratosis

Question 21

red or pink nodule with keratin, ucerated, friable

Answer 21

SCC

Question 22

PTCH tumor suppressor gene associated with

Answer 22

BCC

Question 23

pink or translucent, telangiectatic, rolled border, thin plaque that may be scaly

Answer 23

most likely superficial BCC,
but can be
SCC in situ
actinic keratosis

Question 24

BCC can be

Answer 24

ulcerated
pigmented
sclerosing

Question 25

Hx: scar that periodically bleeds or scabs think

Answer 25

sclerosing basal cell

Question 26

for superficial BCC what treatments can be used

Answer 26

• imiquimod
• 5-FU
• photodynamic therapy

Question 27

which carcinoma is metastasis rare

Answer 27

in BCC