non-hodgkin lymphoma Flashcards

1
Q

what is non- Hodgkin lymphoma

A

cancer that develops in the lymphatic system.
lymphocytes start to multiply in an abnormal way. they collect in the lymph nodes and also lose their ability to fight infection.

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2
Q

cause/risk factors of non-Hodgkin’s lymphoma

A

the exact cause is unknown but the risk factors are:
- a weakened immune system, such as HIV
- autoimmune disease
- infection of epsein-barr virus; this causes glandular fever and may be a trigger for development of type 1 diabetes
- infection with helicobacter pylori, a common bacterial infection that can cause stomach ulcers

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3
Q

treatments of non-Hodgkin’s lymphoma

A

high-grade lymphomas grow quickly and aggressively but respond well to treatment and can often be cured. low-grade lymphomas grow slowly and may not necessarily require immediate medical attention but are harder to cure completely.
- radiotherapy
- chemotherapy
- monoclonal antibody therapy

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4
Q

monoclonal antibody therapy in thyroid cancer

A

uses rituximab. this binds to the CD20 antigen that is present of B lymphocytes and leads to their destruction. once the treatment is over , a new population of healthy B lymphocytes develops from stem cells in the bone marrow.

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