Non Benzo Sedative Hypnotic Agents

Question 1

Eszopidone (Lunesta): used to

Answer 1

Increase total sleep

Decrease amount of time it takes to fall asleep but does not reduce night awakenings

Question 2

Eszopidone (Lunesta): Action and a/e

Answer 2

Action: interacts with GABA receptors

A/e: change in behavior, antegrade amnesia (short term memory loss)

Question 3

Ramelton (Rozerem): Action and a/e

Answer 3

Action: binds to melatonin receptors in CNS to keep circadian rhythm

A/e: arthralgia/myalgia, taste change, decreased testosterone and cortisol and increased prolactin levels

Question 4

Zolpidem (Ambien): A/e

Answer 4

Daytime drowsiness, dizziness nausea, diarrhea and anegrate amnesia

Question 5

Zolpidem (Ambien): What will happen if I stop taking Ambien abruptly?

Answer 5

Rebound insomnia and withdrawal

Question 6

Patient Teaching:How often should I take sleeping pills?

Answer 6

Don’t take them every night because they loose their effect