NMB Reversal Agents

Question 1

Which NMB reversal agent crosses the blood brain barrier?

Answer 1

• Physostigmine (tertiary amine)

- Neostigmine, Edrophonium, and Pyridostigmine are quaternary amines (do NOT cross the BBB)

Question 2

Sugammadex selectively binds to what type of NMBs?

Answer 2

• aminosteroid NDNMB (roc > vec > panc)