Cardiac Pathophysiology Flashcards
Cardiac remodeling d/t heart failure can be reversed by which drugs?
- ACE inhibitors (-pril drugs)
- Aldosterone inhibitors (spironolactone)
What are the dihydropyridine CCBs and what are the targeted effects?
- suffix “-pines”
- vasculature (vasodilation d/t dec Ca+2)
- dec SVR
What are the non-dihydropyridine CCBs and what are the targeted effects?
- verapamil and diltiazem
- targets myocardium > vessels
- dec isotropy, chronotropy, and dromotropy
- dec. SVR
What are examples of aterioldilators and what are the effects?
- hydrazine and SNP
- inc nitric oxide (vasodilation)
- dec SVR
What are examples of ventilators and what are the effects?
- Nitroglycerine and SNP
- inc nitric oxide (vasodilation)
- dec venous return (preload)
In what order to CCBs impair contractility from most to least?
verapamil > nifedipine > diltiazem > nicardipine
In the pt with a decreased EF and the need to preserve contractility, which CCB is better, verapamil or diltiazem?
- diltiazem
What is the best method of diagnosis for a cardiac tamponade?
TEE
What is beck’s triad and what does it represent?
- cardiac tamponade
- Hypotension, JVD, muffled heart sounds
What are the other names of Obstructive Hypertrophic Cardiomyopathy?
- Hypertrophic Obstructive Cardiomyopathy (HOCM)
- Asymmetric Septal Hypertrophy (ASH)
- Idiopathic Hypertrophic Subaortic Stenosis (IHSS)
How can SAM be easily diagnosed?
TEE
What are indications for IABP?
- cardiogenic shock
- MI
- intractable angina
- difficult separation from CPB
What are contraindications to IABP?
- severe aortic insufficient
- descending aortic disease
- severe peripheral vascular disease
- sepsis
What does the inflation of the IABP correlate with on the aortic pressure waveform?
- dicrotic notch
What are the independent risk factors for AAA?
- cigarette smoking
- male gender
- advanced age