Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Inhaled Anesthetics Review > Nitrous Oxide > Flashcards

Nitrous Oxide Flashcards

1
Q

N2O boiling point

A

-88.5 C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

N2O saturated vapor pressure

A

38,628 mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

N2O MAC

A

105 vol%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

N2O blood/gas coefficient

A

0.47

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

N2O brain/blood coefficient

A

1.1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

N2O muscle/blood coefficient

A

1.2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

N2O fat/blood coefficient

A

2.3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

N2O Respiratory effects

A

Least decrease in tidal volume & increase in end tidal CO2 out of gases (Minimal compared to potent agents)
Reduces ventilatory response to hypoxia & hypercapnia
Additive respiratory depressant with other agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

N2O CV effects

A

Direct negative inotrope
No substantial effect on LV diastolic function
Slight decrease in CO
Modest increase in pulmonary & systemic arterial pressure (increase arterial vasomotor tone) via a sympathomimetic effect - counteracts hypotensive effects of all other agents
Increases circulating norepi levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

N2O Obstetrical effects

A

decreases activity of methionine synthetase & thymidylate synthetase - important for RNA/DNA replication - has been linked with miscarriages if N2O inappropriately scavenged

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

N2O Discovery

A

1760s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does N2O effect MAC of other anesthetics

A

Each 1 vol% added to inspired gases, 1 vol% less potent inhalation agent may be administered

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

N2O concentration effect

A

Leaves less space in FRC for fresh gas inflow to occur- as fresh gas saturated with anesthetic flows in the concentration of anesthesia in FRC increases faster

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

N2O second gas effect

A

Not a big deal with sevo/des. Potent inhalation agent rises to higher concentration more quickly because of concentration effect.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

N2O Diffusion Hypoxia

A

N2O washes out fast due to coefficients, as N2O rushes into lungs to leave, it drags other gases with it & displaces O2 which can results in diffusion hypoxia. (just turn on oxygen, should be fine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

N2O CNS effects

A

Inconsistent data - believed to increase CBP so increase ICP & CMRO2. May be attenuated by hypocapnia
Decreases seizure activity

17
Q

N2O renal effects

A

Decreases renal blood flow, GFR & urinary output

18
Q

N2O Complications

A

Contraindicated in patients with tympanic membrane/ear surgeries (*tympanoplasties), pneumothoraces (will double in size in 10 minutes, triple in 30 minutes), small bowel obstructions, pneumocephalus, air emboli (increase in pressure in spaces that cannot increase in size, increase in volume in spaces that can increase in size)

19
Q

NIOSH standards of N2O in ambient OR air

A

<25 ppm

20
Q

N2O liver:blood coefficient

A

0.8

Inhaled Anesthetics Review (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions