Nitrates Flashcards

1
Q

Use and action:

A

Used in angina, and is a potent vasodilator

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2
Q

Side effects and caution:

A

Flushing, headache and postural hypotension

Tolerance

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3
Q

Formulations:

A

Sublingual tablet
Aerosol spray
Transdermal patches (longer DOA) *increased risk of tolerance - leave patch off for 8-12 hours

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4
Q

MR prep dinitrate (up to 12 hours)

A

TWICE DAILY

- give after 8 hours instead of 12 hours to reduce tolerance

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5
Q

Isorsobide mononitrate MR prep

A

ONCE DAILY

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6
Q

Sublingual GTN tablets

A

(300, 500 and 600mcg)
Glass container
Foil line cap, no cotton wadding
Discard after 8 weeks

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