ACEi

Question 1

Indications?

Answer 1

HF, hypertension, diabetic nephropathy and prophylaxsis of CV events

Question 2

Contraindicated in:

Answer 2

Aliskiren - renin inhibitor (with patients with diabetes due to risk of hyperkalaemia) and those with an eGFR <60ml/min

Question 3

Cautions:

Answer 3

Afro-carribean patients, use of diuretics and first dose hypotension give at bed-time
Avoid in pregnancy

Question 4

Heart failure:

Answer 4

Beta-blockers + ACEi

Question 5

Side effects:

Answer 5

Alopecia, angioedema, persistent dry cough, skin reactions, GI effects, constipations, electrolyte imbalance

Question 6

Renal monitoring

Answer 6

Check renal/electrolytes prior - hyperkalaemia - more common in RI
NSAIDs can increase risk of renal damage - avoid in kidney disease