NIH Flashcards
of NIH Institutes and Centers
27
Each awarding Institute/Center (I/C) has its own mission and priorities, budget and funding mechanisms
NIH Scientific Review Officer
Responsible for scientific and technical review
Point of contact for applicants during the review process
NIH Program Official
Responsible for the programmatic, scientific and/or technical aspects of the grant
Provides scientific guidance to investigators pre- and post- award
Develops initiatives
Provides post-award oversight
NIH Grants Management Officer
Responsible for completion of business management requirements
- evaluates applications for administrative content and compliance with policy
- negotiates awards
- interprets grants admin policies
Types of NIH Funding
Research Award Programs (R-Series) - R01, R03, R15, R21, R56
Resource Grants - R24, R25, X01
Research Training Grants and Fellowships (T and F) - T32, T35, F31, F32, F33
Cooperative Agreements (U Series) - U01, U13
Program Project / Center Grants (P Series) - P01, P20, P30, P50
NIH Research Project Grant Program (R01)
- NIH’s most commonly used grant program
- No specific dollar limit unless specified in FOA
- Advance permission required to request $500k or more (direct costs) in any year
- Generally 3-5 years
- All ICs utilize
- Typically uses a modular budget
NIH Small Grant Program (R03)
- Limited funding for short periods for projects aimed at collecting data, developing new technology
- Limited to 2 years of funding
- Direct costs up to $50k per year
- Utilized by ~ half of ICs
NIH Support for Conferences and Scientific Meetings (R13 and U13)
- Support for high quality conferences/meetings that are relevant to NIH’s scientific mission and public health
- Requires advance permission
- Award amounts vary by IC
- Up to 5 years
NIH Academic Research Enhancement Award (AREA or REAP) (R15)
- Supports small-scale research projects at educational institutions that provide baccalaureate or advanced degrees but have not been major recipients of NIH support
- Direct costs limited to $300k over entire project period
- Project period limited to 3 years
NIH Exploratory/Developmental Research Grant Award (R21, R33)
- Provides support in early stages of development; sometimes used for pilot and feasibility studies
- Limited to 2 years
- Combined direct costs for 2 year project period usually cannot exceed $275k total
- The R33 is the 2nd phase of support for research initiated under the R21
- Designed to permit early peer review of the rationale for the proposed clinical trial and support development of essential elements of a clinical trial
- Usually 1 year, cannot exceed 3 years
- Direct costs cannot exceed $100k per year
- Modular budget required
- Only used by select ICs
NIH Clinical Trial Planning Grant (R34)
NIH Small Business Technology Transfer (STTR) (R41/R42)
- 3 phase structure (know the phases)
- Eligibility limited to U.S. small business concerns
- PD/PI may be employed by the SBC or the participating non-profit research institution as long as he/she has a formal appointment with SBC
- Multiple PDs/PIs allowed
NIH Small Business Innovative Research (SBIR) (R43/R44)
- 3 phase structure (know phases)
- Eligibility limited to U.S. small business concerns
- Primary employment of PD/PI must be with the small business concern.
- Multiple PDs/PIs allowed
- All ICs utilize except FIC
NIH
Used in a wide variety of ways to provide resources for problems where multiple expertise is needed to focus on a single complex problem in biomedical research or to enhance research infrastructure.
- Also classified as a resource grant.
NIH Resource-Related Research Projects (R24)
NIH Education Projects (R25)
- To promote an appreciation for and interest in biomedical research, provide additional training in specific areas, and/or to develop ways to disseminate scientific discovery into public health and community applications
- Also classified as a resource grant.
- Invites eligible institutions to seek access to NIH research resources
- Also categorized as a resource grant
NIH Resource Access Program (X01)
NIH K01
- Most common early career award
- PI must be a U.S. citizen or non-citizen national of U.S. or permanent resident of U.S.
NIH K99/R00
- “Pathway to Independence (PI) Award”
- Provides up to 5 years of support consisting of 2 phases:
Phase 1 - provides 1-2 years of mentored support for highly promising, postdoctoral research scientists
Phase 2 - provides up to 3 years of independent support contingent on securing an independent research position - Award recipients are expected to compete successfully for independent R01 support from NIH during the career transition period
- Foreign institutions are not eligible to apply
- For K99/R00: PI can be a non-U.S. citizen
Ruth L. Kirschstein National Research Service Awards for Individual Fellowships (F series) and Training Grants (T series)
Predoctoral - F31 and T01, T32, T35 Postdoctoral - F32 and T32 Senior Fellows - F33 Stipends are determined each year by NIH For K and T grants F&A is usually limited to 8% For F grants no F&A
Research Project Cooperative Agreement (U01)
- Used when substantial programmatic involvement is anticipated between the awarding Institute and Center
- One of the many types of Cooperative agreements
- No funding limit unless specified in FOA
Support for broadly based, multidisciplinary, often long-term research programs with a specific objective or theme
Involve a number of independent investigators who share knowledge and common resources
No specific dollar limit unless specified in FOA
Research Program Project Grant (P01)
Often used to support planning activities associated with large multi-project program project grants
Exploratory Grants (P20)
