Nicotinic Antagonists

Question 1

nicotonic antagonists are

Answer 1

neuromuscular blockers action at neuromuscular junction

Question 2

nicotinic anatagonists MOA

Answer 2

non depolarizing or depolarizing

Question 3

movement of calcium in and out of the cell causes

Answer 3

contraction of the muscle or depolarization

Question 4

the end result of depolarizing and non-depolarizing is the same,

Answer 4

paralysis of the muscle

Question 5

depolarizing nicotinic antagonist prototype

Answer 5

succinylcholine - fast acting - transient contractions

Question 6

what gets rid of succinycholine in the body

Answer 6

pseudocholinesterase

Question 7

when would you use succinycholine

Answer 7

intubation or ECT or endoscopy (in and out of the body very quickly - rapid action)

Question 8

neuromuscular blockers have a + charge meaning

Answer 8

they don’t cross the blood-brain barrier

Question 9

**if you only get a neuromuscular blocker are you conscious or unconscious

Answer 9

conscious but completely paralyzed - never given alone!

Question 10

succinylcholine plus an inhaled agent if person is genetically susceptible can cause

Answer 10

malignant hyperthermia (high temp)