Nicotine Cessation Medications

Question 1

Why is nicotine considered the most addictive drug to quit?

Answer 1

It is so lipid-soluable that it goes straight to the brain causing a quick and instant high. It has a fast onset.

Question 2

How many Americans are smokers?

Answer 2

1 in 5

Question 3

What cholinergic receptors does nicotine bind to?

Answer 3

NicotinicN

Question 4

What do NicotinicN receptors do in the cerebrovascular?

Answer 4

Increase BP and cardiac work

Question 5

What do NicotinicN receptors do in the GI?

Answer 5

Increase sections and mobility

Question 6

What do NicotinicN receptors to in the CNS?

Answer 6

Increase alertness, memory, and cognition
Decrease appetite
Activate brain’s pleasure system

Question 7

How long before clients experience nicotine withdrawal?

Answer 7

Within 24 hours

Can last weeks to months

Question 8

Is it better to quit abruptly to gradually?

Answer 8

Abruptly

Question 9

Common withdrawal symptoms

Answer 9

Craving
Nervousness
Irritability
Insomnia
Impaired concentration
Increased appetite
Weight gain

Question 10

What is the best way to quit?

Answer 10

10% quit cold-turkey

20% quit using medications

Question 11

Nicotine Patches

Answer 11

Reduce cravings
Help maintain abstinence
Not carcinogenic

Question 12

Bupropion SR

Answer 12

Mechanism of action unclear
Reduces cravings and withdrawal
Adverse effects are mild

Question 13

Varenicline

Answer 13

Partial agonist at nicotinic receptors
Decreases the reward of nicotine
Reduces cravings and withdrawal

Question 14

Most serious side effect of varenicline

Answer 14

Mood changes that can lead to suicidal ideation

Also, nausea in 30-40% of users

Question 15

What can double the cessation success rate?

Answer 15

Medications