nice to know Flashcards

1
Q

Hormone dependent tumor

A

breasr, prostate, endometrium, thyroid, kidney, ovary, bone, testis

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2
Q

malignancy having double peak

A

npc, lymphoma, osteosarcoma

Ewings, thyroid

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3
Q

auto regressive tumor

A

malignant melanoma, choriocarcinoma, rcc, nephroblastoma, burkitts lymphoma
Neuroblastoma

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4
Q

~~~
lymphnode sample in different cancer
Breast, colorectum, stomach, oesophagus

A

10-12-16-22

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5
Q

Female predominant tumor

A
Meningioma
Thyroid
Cervical oesophagus
Colon
Post cricoid region
Glomus tumor
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6
Q

Locally malignant tumor

A
Ameloblastoma
Bcc
Craniopharyngioma
Desmoid tumor
Germ cell tumor
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7
Q

Radiosensitive tumor

A
MEWLS
myeloma
Ewings
Wilms
Lymphoma 
Seminoma
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8
Q

extragonadal site for germcell tumor

A
pineal gland
thyroid, rare
mediastinum
retroperitoneal
sacrum, rare
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9
Q

retroperitoneal organ

A
sadpucker
suprarenal gland
aorta
duodenal 2nd/3rd part
pancreas
ureter
colon
kidney
esophagus
rectum
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10
Q

Dna virus causing cancer

A

Hpv 16, 18, 31,32
Hbv
Ebv
Kaposis sarcoma

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11
Q

Rna virus causing cancer

A

Hcv

Htlv

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12
Q

Genetic predisposition of autosomal dominant

A
Ca breast ovary
Neurofibromatosis
Fapc
Men syndrome
VHL disease
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13
Q

Oncogenes

Protooncogenes

A

Tgf-A: hcc astrocytoma

Erbb1,2- lunh, breast, ovary

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14
Q

RET

KIT

A

Ret: MEN 2A,2B

KIT-GIST, seminoma

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15
Q

Ras gene responsible for

A

Kras- colon lung
Hras:-bladder kidney
Nras:-melanoma

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16
Q

Myc gene

A

C myc: burkitts lymphoma
N myc: neuroblastoma, sclc
L myc: sclc

17
Q

Cyclin responsible for

A

Cyclin d:- mantle cell

Cyclin E :- breast

18
Q

indication of rt in non malignant conditions

A
axillary sweat gland abscess
chronic and acute osteoarthritis
post operative prophylaxis of keloid pterygium
graves arthropathy
a-v malformation
benign tumor---
pitutary adenoma
meningioma
glioma
vestibular schwannomas
glomas tumor
chordoma
craniopharyngioma
others
splenomegaly
plantar warts
19
Q

Stereotactic radiotherapy used for

A
Meningioma
Pitutary tumor
Acoustic neuroma
Metastatic brain lesion
Glioma
Others:
AVM
Trigeminal neuralgia
20
Q

Drugs crossing bbb

A
Cyclophosphamide
Mtx
Temozolomide
Carmustine
Lomustine
Vcr
Procarbazine
21
Q

Oral chemo

A
Capecitabine
Erlotinib
Gefitinib
Mtx
Anastrozole
Letrozole
Flutamide
Megestrol acetate
22
Q

Radiosensitizing drug

A
Cpl
5fu
Doxorubicin
Paclitaxel
Docetaxel
Mitomycin 
Vincristine
Temozolomide
Nimorazole
Metronidazole
23
Q

Tumor that doesnt require biopsy to treat

A

Brain e 6 condition:

  1. Brain mets with multiple lesion
  2. Active systemic cancer
  3. brainstem glioma
  4. Optic nerve meningioma
  5. Primary CNS lymphoma with HIV + pt, EBV + in CSF
  6. Secretory germ cel tumor
24
Q

4 most ematogenic drug

A

Carmustine, Cisplatin, Doxorubicin, Dacarbazine.