nice to know Flashcards
Hormone dependent tumor
breasr, prostate, endometrium, thyroid, kidney, ovary, bone, testis
malignancy having double peak
npc, lymphoma, osteosarcoma
Ewings, thyroid
auto regressive tumor
malignant melanoma, choriocarcinoma, rcc, nephroblastoma, burkitts lymphoma
Neuroblastoma
~~~
lymphnode sample in different cancer
Breast, colorectum, stomach, oesophagus
10-12-16-22
Female predominant tumor
Meningioma Thyroid Cervical oesophagus Colon Post cricoid region Glomus tumor
Locally malignant tumor
Ameloblastoma Bcc Craniopharyngioma Desmoid tumor Germ cell tumor
Radiosensitive tumor
MEWLS myeloma Ewings Wilms Lymphoma Seminoma
extragonadal site for germcell tumor
pineal gland thyroid, rare mediastinum retroperitoneal sacrum, rare
retroperitoneal organ
sadpucker suprarenal gland aorta duodenal 2nd/3rd part pancreas ureter colon kidney esophagus rectum
Dna virus causing cancer
Hpv 16, 18, 31,32
Hbv
Ebv
Kaposis sarcoma
Rna virus causing cancer
Hcv
Htlv
Genetic predisposition of autosomal dominant
Ca breast ovary Neurofibromatosis Fapc Men syndrome VHL disease
Oncogenes
Protooncogenes
Tgf-A: hcc astrocytoma
Erbb1,2- lunh, breast, ovary
RET
KIT
Ret: MEN 2A,2B
KIT-GIST, seminoma
Ras gene responsible for
Kras- colon lung
Hras:-bladder kidney
Nras:-melanoma
Myc gene
C myc: burkitts lymphoma
N myc: neuroblastoma, sclc
L myc: sclc
Cyclin responsible for
Cyclin d:- mantle cell
Cyclin E :- breast
indication of rt in non malignant conditions
axillary sweat gland abscess chronic and acute osteoarthritis post operative prophylaxis of keloid pterygium graves arthropathy a-v malformation benign tumor--- pitutary adenoma meningioma glioma vestibular schwannomas glomas tumor chordoma craniopharyngioma others splenomegaly plantar warts
Stereotactic radiotherapy used for
Meningioma Pitutary tumor Acoustic neuroma Metastatic brain lesion Glioma Others: AVM Trigeminal neuralgia
Drugs crossing bbb
Cyclophosphamide Mtx Temozolomide Carmustine Lomustine Vcr Procarbazine
Oral chemo
Capecitabine Erlotinib Gefitinib Mtx Anastrozole Letrozole Flutamide Megestrol acetate
Radiosensitizing drug
Cpl 5fu Doxorubicin Paclitaxel Docetaxel Mitomycin Vincristine Temozolomide Nimorazole Metronidazole
Tumor that doesnt require biopsy to treat
Brain e 6 condition:
- Brain mets with multiple lesion
- Active systemic cancer
- brainstem glioma
- Optic nerve meningioma
- Primary CNS lymphoma with HIV + pt, EBV + in CSF
- Secretory germ cel tumor
4 most ematogenic drug
Carmustine, Cisplatin, Doxorubicin, Dacarbazine.
