neutropenic FUO Flashcards
1
Q
who is the classic neutropenic pt
A
received cytotoxic or immunosuppressive agent for under lying dz (but many other causes)
2
Q
what is the neutrophil count at which pts become susceptible to infxn? What is the definition of neutropenia
A
susceptible at 1000/uL, but neutropenia is 500/uL
3
Q
prognosis of neutropenic FUO is poor unless these 3 conditions occur
A
initial neutrophil ct >500, neutropenia resolves with tx, pathogen is GN
4
Q
what is the empiric tx for neutropenic FUO
A
broad spec PCN + AG (OR 4th gen cephalo ONLY) + Neupogen (granulocyte colony stimulating factors)
5
Q
second line tx for neutropenic FUO
A
addition of anti-fungal after 3 days unresolved fever
