Neurovirology Flashcards
1
Q
Cranial nerves
A
Nerves that emerge from the brain to relay info to the rest of the body
Good route for infection into nervous system
2
Q
Olfactory nerve
A
3
Q
Trigeminal nerve
A
4
Q
Glossopharyngeal nerve
A
5
Q
RNA viruses
A
Poli, rabies, measles
6
Q
DNA viruses
A
CMV, JC, VZV
7
Q
Viral route of infection in neurons
A
Axon terminals
Try to get to cell body to replicate
8
Q
2 types of neuron entry for viruses
A
Transneuronal
Hematogenous
9
Q
Transneuronal
A
10
Q
Hematogenous
A
11
Q
Retrograde transport
A
Towards cell body
11
Q
Retrograde transport
A
Towards cell body
12
Q
Anterograde transport
A
Away from cell body
13
Q
Measles
A
-ssRNA genome encoding 8 proteins
non-lytic
14
Q
What cells does measles infect?
A
Neurons, brain capillaries and monocytes
15
Q
Rabies virus
A
enveloped and bullet shaped
linear -ssRNA 12kb
16
Q
Rabies dissemination route
A
5 steps
