Neurovirology Flashcards

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1
Q

Cranial nerves

A

Nerves that emerge from the brain to relay info to the rest of the body
Good route for infection into nervous system

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2
Q

Olfactory nerve

A
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3
Q

Trigeminal nerve

A
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4
Q

Glossopharyngeal nerve

A
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5
Q

RNA viruses

A

Poli, rabies, measles

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6
Q

DNA viruses

A

CMV, JC, VZV

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7
Q

Viral route of infection in neurons

A

Axon terminals
Try to get to cell body to replicate

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8
Q

2 types of neuron entry for viruses

A

Transneuronal
Hematogenous

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9
Q

Transneuronal

A
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10
Q

Hematogenous

A
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11
Q

Retrograde transport

A

Towards cell body

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11
Q

Retrograde transport

A

Towards cell body

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12
Q

Anterograde transport

A

Away from cell body

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13
Q

Measles

A

-ssRNA genome encoding 8 proteins
non-lytic

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14
Q

What cells does measles infect?

A

Neurons, brain capillaries and monocytes

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15
Q

Rabies virus

A

enveloped and bullet shaped
linear -ssRNA 12kb

16
Q

Rabies dissemination route

A

5 steps