Bacterial Virology Flashcards
1
Q
PhiX174 structure
A
+ssDNA circular
Bacteriophage
Icosahedral, enveloped
infects E.coli
2
Q
Pseudomonas Phi6 structure
A
Lipid membrane around nucleocapsid
P6 + P3 spike complex
Infects pseudomonas
3
Q
Lambda phage structure
A
infects e.coli
4
Q
T4 phage structure
A
Icosahedral head + tail w tail fibres
Infects E.coli
5
Q
Rolling circle replication steps
A
6
Q
Pseudomonas phi 6 replication
A
Semi-conservative replication in the core
7
Q
How do bacteriophages cause disease?
A
Lysogenic phages that contain toxin gene and integrate in host genome
8
Q
Cholera toxin
A
CTX phage
Vibrio cholerae
G protein receptor system affected in intestinal cells
9
Q
Shiga toxin
A
Severe intestinal disease
Lambda virus infects E.coli
