Neurotransmitters - Inhibitory Flashcards
GABA
location: most abundant NT in CNS, cytoplasm of presynaptic neurons, cortex, thalamus, brainstem, posterior hypothalamus
function: motor control, vision, alertness, anxiety, inhibits motor, sensory and cognitive neurons –> sedation, muscular/cardiorespiratory relaxation and pain inhibition
receptor: ionotropic and metabotropic
agonist/antagonist
glycine
location: synthesized from serine, found in proteins, brainstem and spinal cord
function: spinal interneurons inhibition, healthy digestive system, helps prevent breakdown of muscle, protects kidneys from harmful side effects of drugs
receptor: ionotropic
agonist/antagonist
serotonin
location: produced by raphe nuclei, stored in synaptic vesicles and platelets
function: stabilize mood, controls bowel movements, sleep, nausea, wound healing, bone health
receptors: ionotropic and metabotropic
agonist/antagonist
