Neurotransmitters in Relation to Movement Disorders Flashcards
1
Q
Where is dopamine produced?
A
Substantia Nigra
2
Q
What does dopamine do?
A
Excited direct pathway via D1 receptors and inhibits indirect pathway via D2 receptors
3
Q
What causes PD?
A
Loss of DA neurons in the substantia nigra
4
Q
What does ACh do?
A
Inhibit direct pathway and excite indirect pathway
5
Q
What causes Huntington’s Disease?
A
Loss of cholinergic interneurons in the striatum
