CNS Neurotransmitters Flashcards

1
Q

What are the criteria for accepting a substance as a transmitter?

A
  1. synthesised in neuron and the enzymes are present in the neuron
  2. released in sufficient quantity to elicit a response
  3. removal or inactivation must exist
  4. mimic action of endogenously released neuro-trans when administered exogenously
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2
Q

What are the 2 types of neurotransmitter receptors?

A

Ligand-gated ion channels and metabotropic (G-protein coupled receptors) intracellular

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3
Q

What are the 3 methods of clearing a neurotransmitter?

A

Diffusion, reuptake and degradation

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