Neurotransmitters Flashcards
Neuromodulators
- if they diffuse over long distances, affecting many cells, not necessarily triggering firing but ALTERING LIKELIHOOD
Neurotransmitters
- if impact nearby neurons
Hormones
same chemicals as Neuromodulators but called hormones when found circulating the bloodstream
Acetylcholine
- ACh
- important NT in PNS
- e.g. muscle movement (contraction)
- also throughout brain for AROUSAL
- EXCITATORY
- released by the basal forebrain
- memory, recall, arousal throughout the cortex
GABA
- most abundant INHIBITORY NT (Opens Cl- gates)
- suppresses cortical activity
- regulates anxiety, relaxes the brain
Glutamate
- most abundant EXCITATORY NT
- opens Na+ gates
- Roles in perception, memory, schizophrenia
-
Serotonin
- 5-HT
- many different kinds, involved in sleep, mood regulation
The Catecholamines
- Dopamine (DA), Norepinepherine (NE) & Epinepherine
- involved in arousal, depression, reinforcement, motor control
- often act as Neuromodulators
- Substance P
- Endorphins
Substance P
a peptide (complex protein) released from Pain receptors
Endorphins
a peptide w/opiate effects
i.e. pain suppression, reinforcement
produced in “runner’s high”
“Endorphin” = “Endogenous Morphine”
Hormones
e.g. Testosterone, Estrogen, Oxytocin, Insulin, Cortisol, Epinepherine (Adrenalin) etc.
released by brain cells or glands, act as NTs, NMs, or circulate in blood,
affect Neurons, Muscles, Organs
Same NTs can have VERY DIFFERENT…..
…. physiological and behavioral EFFECTS in different parts of the brain/body