Neurotransmitters Flashcards
Enzyme that breaks down many neurotransmitters at the synaptic junction.
Monoamine oxidase
What does reuptake mean?
After a neurotransmitter has delivered its message at the synaptic junction, it will be STORED FOR FUTURE USE or destroyed.
What are some roles of dopamine?
Excitatory neurotransmitter.
Pleasure and reward.
Stress can decrease dopamine levels.
Transmits mostly in brain stem.
Transmits complex movements, emotions, cognition.
What is dopamine made from?
Amino acid called tyrosine (from diet)
What neurotransmitter is higher than normal in schizophrenia?
Dopamine
Many schizo meds aim to regulate dopamine
What are some roles of serotonin?
Inhibitory neurotransmitter.
Emotional regulation
Sexual behavior
Temp regulation
Sleep
Pain management
What is unique about serotonin?
It has many more receptor sites than all the other neurotransmitters.
Complex transmitter with major role in anxiety, mood, depression, psychosis.
What is role of norepinephrine?
Excitatory
Mood
Sleep
Memory
Attention
Learning
Low levels of norepinephrine manifest as what?
Social withdrawal
Depression
Anxiety
Memory loss
What is role of GABA?
Amino acid that serves as a inhibitory neurotransmitter.
Modulates other Neurotransmitters
Increased levels make you drowsy
Benzos enhance GABA action
What is role of histamine?
Regulates other neurotransmitters
What is role of glutamate?
Excitatory NT
Works closely with dopamine
Regulates motor and cognitive function
What is role of acetylcholine?
Inhibitory and excitatory NT
Controls skeletal muscle
Regulates sleep/wake cycle
Alzheimers patients have LOW acetylcholine and have decreased muscle/cognitive control. Given acetylcholine to treat
