Mood Disorders Flashcards
What is difference between mood and affect?
Mood=how a person feels
Affect=observable behavior
What is the difference between major depressive disorder and persistent depressive disorder?
MDD more debilitating.
PDD is longer with less severe symptoms. These people are usually functioning but not optimally.
What are the two major mood disorders?
Depressive
Bipolar
What is anhedonia?
Inability to find pleasure in things
What are risk factors for depression?
Family history
History of suicide
LGBTQ
Female
>40 yo
Chronic medical problems (especially chronic pain type illnesses)
No social support
Alcohol/Drug abuse
Early trauma
Sex abuse history
Post partum
What is the depression symptoms acronym?
SIG E CAPS
S=Sleep disturbance
I=Interest diminished (anhedonia)
G=Guilt
E=Energy decreased
C=Concentration loss
A=Appetite changes
P=Psychomotor retardation
S=Suicidal
Which class of anti-depressants have the highest risk of suicidal ideas and aggressive behavior in adolescents?
SSRIs
What are the drugs in the SSRI class?
CitaloPRAM
EscitaloPRAM
FluoxetINE
FluvoxamINE
ParoxetINE
SertralINE
What are common side effects of SSRIs and SNRIs?
Headache
GI disturbance
Insomnia/Fatigue
Anxiety
Sexual dysfunction
Agitation/Jittery
Increased bleeding risk
What are serotonin syndrome signs?
Acronym=SHIVERS
S=Shivering
H=Hyperreflexia
I=Increased temp
V=Vital Sign changes
E=Encephalopathy
R=Restlessness
S=Sweating
How do we treat serotonin syndrome?
Muscle relaxants
Cyproheptadine (blocks serotonin)
Meds to slow HR and lower BP
Supportive=lower temp and O2 and IV fluids
What are the drugs classed as SNRIs?
VenlaFAXINE
DesvenlaFAXINE
Duloxetine
Levomilnacipran
What are some common atypical antidepressants?
Trazadone
Mirtazapine (Remeron)
Bupropion
What are the two common suffixes for TCA?
-Triptyline
-Pramine
What are the most common side effects in TCAs?
Anti-cholinergic
Weight gain
Orthostatic hypotension
Sedation
Nausea
–These usually resolve on own–
What are some things to remember about TCAs?
They interfere with many meds.
They can be cardiotoxic.
They take 4-8 weeks to work.
Foods high in tyramine + MAOI can lead to what? What are s/sx of this?
Hypertensive crisis
S/Sx:
Headache/blurry vision
Chest pain/tachycardia
SOB
Diaphoresis and anxiety
Confusion
N/V
What are some food high in tyramine?
Anything pickled, fermented or smoked
Cheese
Beer/Wine
Soy products
Ripe avocados and figs
OK Foods in SMALL amounts:
Caffeine
Chocolate
Ginseng
