neurotransmitters Flashcards
First neurotransmitter to be identified
acetylcholine
Involved in REM sleep initiation
Acetylcholine
neurotransmitter of central neurons involved in learning and memory
Acetylcholine
synthesized from tyrosine
DA, NE, Epi
prolactin suppression
dopamine
Increased in addiction, schizophrenia, ADHD,
dopamine
mood disorders, stress and anxiety, PTSD, ADHD, orthostatic tachycardia syndrome
Norepinephrine
Mood and anxiety disorders, vomiting, migraine pain pathway, sleep/wake, arousal
Serotonin
Myesthenia gravis, Alzheimer disease, Parkinson, nicotine addiction
Acetylcholine
Inadequate inhibition can predispose to seizures/epilepsy
GABA
Deficits could contribute to anxiety disorders
GABA
Excitotoxicity: neuron death after stroke, brain injury, and neurodegenerative disorders
glutamate
Slow modulatory effects, mediated by metabotropic receptors
amine transmission
parasympathetic postganglionic neurons
acetylcholine
neurotransmitter of all motor neurons
acetylcholine
Found in midbrain substantia nigra and ventral tegmental area (VTA) and hypothalmus
Dopamine
Degeneration of substantia nigra DA neurons in the striatum
Parkinson disease
found in pons and medulla
Norepinephrine (NE)
project widely to cortex, hypothalamus, cerebellum, and spinal cord
NE
Strongly implicated in behavioral control, attention/focus, and sympathetic activation
NE
Aggression modulation
serotonin
Major role of hypothalamic histamine
initiation and maintenance of waking