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neuro Flashcards

1
Q

amino acid used to build proteins

A

glutamate

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2
Q

Major glutamate ionotropic receptors

A

AMPA

NMDA

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3
Q

Activation increases sodium and calcium permeability leading to rapid depolarization and increased intracellular calcium

A

NMDA )n-methyl-D-aspartate

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4
Q

Activation increases sodium permeability leading to rapid depolarization

A

AMPA (a-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate)

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5
Q

Causes rapid depolarization and action potential generation in postsynaptic neurons

A

Glutamate

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6
Q

the main excitatory transmitter of the brain

A

Glutamate

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7
Q

Ligand-gated ion channels

A

ionotropic receptors

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8
Q

receptors with selectivity for sodium, potassium, or calcium

A

Excitatory ionotropic receptors

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9
Q

G-protein-coupled receptors that create slower changes in membrane potential

A

Metabotropic receptors

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10
Q

Receptors selective for chloride

A

Inhibitory ionotropic receptors

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11
Q

principal inhibitory transmitter

A

GABA

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12
Q

slow transmission with only metabotropic receptors

A

Amines and peptides (expect 5-HT type 3 serotonin)

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13
Q

neurotransmitters with rapid transmission by ionotropic receptors responsible for sensory, motor, reflex

A

Glutamate, GABA, Acetylcholine

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14
Q

neuromuscular transmission, parasympathetic visceral control, central modulatory actions

A

Acetylcholine

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15
Q

motor, endocrine, motivational control

A

Dopamine

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16
Q

Sympathetic visceral control, central arousal, stress responses

A

Norepinephrine

17
Q

Central food intake regulation, arousal, mood modulation

A

Serotonin

18
Q

initiates the wake state

A

Histamine

19
Q

two main postsynaptic GABA receptors

A

GABAa - Ionotropic with pore permeable to chloride

GABAb - metabotropic with inhibitory effects due to K+ channel opening and Ca+ channel closing

20
Q

Potential mechanisms of Epilepsy

A

Too much excitation - excessive glutamate - sodium and calcium channels

Too little inhibition - inadequate GABA - reduced activity of chloride and potassium channels

21
Q

rapid and abundant AMINO ACID transmitters

A

Glutamate and GABA

22
Q

Amine Transmitters

A

Acetylcholine
catecholamine (DA and NE)
Serotonin (5-HT)
Histamine

Nervous system (5 decks)

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