Neurophysiology 5: Motor System (Lecture 79) Flashcards

1
Q

What is the function of the cerebellum?

A

Coordinates timing and smooth movements

DOES NOT INITIATE MOVEMENT (instead it corrects errors)

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2
Q

The cerebellum in conjunction with the vestibular system helps maintain ______ _____. It also helps regulate muscle ________.

A

Vestibular system
Tone

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3
Q

What is the importance of cerebellar peduncles?

A

Path for cerebellar efferents and afferent

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4
Q

Cerebellar afferents coming from the spinal cord are what pathways/which info?

A

Spinocerebellar and spinocuneocerebellar pathways
Proprioceptive information and LMN

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5
Q

Cerebellar afferents coming from the cerebral cortex are what pathways/which info?

A

Corticopontocerebellar pathway
Motor plan

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6
Q

Cerebellar afferents coming from the brain stem are what pathways/which info?

A

Extrapyramidal action, eyes, ears
Brainstem UMN, tectum and vestibular nuclei

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7
Q

What is the function of the spinocerebellum? Where does it send info to?

A

Coordinated movement and posture
Sends info to brainstem UMN

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8
Q

What is the function of the pontocerebellum? Where does it send info?

A

Coordinated and properly timed skilled movement (limbs)
To motor cortex

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9
Q

What is the function of vestibulocerebellum? Where does it send info?

A

Coordinated balance and eye movement
To vestibular nuclei

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10
Q

Where are cerebellar efferents?

A

Deep cerebellar nuclei

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11
Q

Cerebellar efferents do NOT have _____ ______ path. Meaning it is unable to initiate ______ or directly impact muscle ______.

A

Descending spinal path

Movement

Strength

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12
Q

What is hypermetria?

A

Toy soldier walk

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13
Q

What is ataxia?

A

Spinal walk

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14
Q

What are signs of cerebellar dysfunction in spinocerebellar?

A

Hypermetria and ataxia

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15
Q

What are signs of cerebellar dysfunction in pontocerebellar?

A

Intention tremors

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16
Q

What are signs of cerebellar dysfunction in vestibulocerebellar?

A

Wide based stance

17
Q

Where is the vestibular apparatus? What is the function? What receptor does it house?

A

Located in the inner ear

Sets body equilibrium or balance

Houses the receptor organs for detecting head position and movement

18
Q

The vestibular apparatus stabilizes what and coordinates what?

A

Stabilizes position of the head and trunk

Coordinates eye movements

19
Q

Where are the receptors found in the vestibular apparatus?

A

Three semicircular ducts
Vestibule

20
Q

Which receptor if found in the three semicircular ducts? What does it sense?

A

Crista apmullaris

Sense angular acceleration

21
Q

What are the receptors found in the vestibule? What do they sense?

A

Macula saccule and macula utricle

Sense static equilibrium/balance and linear acceleration

22
Q

What is the 1st order neuron in the vestibular apparatus? What is the 2nd order neuron?

A

1st : vestibulocochlear nerve and vestibular ganglion
2nd: vestibular nuclei in medulla

23
Q

Describe the structure of crista ampullaris

A

Bathed in endolymph (high in K)
Hair cells embedded in gelatinous cupola
Lag behind endolymph during movement
Sterocilia tip toward kinocilium to induce AP

24
Q

How does the crista ampullaris induce AP

A

Stereocilia tip toward kinocilium to induce AP

25
Q

Describe the structure of the macula saccule and macula utricle

A

Hair cells imbedded in gelatinous layer with otholiths
Otholiths (ear rocks) weigh down membrane and stimulate hair cells

26
Q

What are the vestibular nuclei projections?

A

Vestibulospinal tract
Medial longitudinal fasciculus
Cerebellum
Emetic Center

27
Q

How does the vestibulospinal tract function?

A

Ipsilateral ventral funiculus
Activates extensor and inhibits flexors

28
Q

Where does the medial longitudinal fasciculus go to? What is the function?

A

Goes to CNS III IV VI which innervate extraocular muscles

Helps eye fix on target- ‘Gazes stabilization’

29
Q

What are the two pathways from vestibular system to cerebellum?

A

Direct: primary vestibular axons to cerebellar flocculonodular lobe
Indirect: vestibular nuclei project to cerebellar flocculonodular lobe

30
Q

What is the peripheral vestibular subdivision?

A

Receptors (hair cells), vestibular nerve (inner ear structure)

31
Q

What is the central vestibular subdivision?

A

Brain stem and cerebellar vestibular structure

32
Q

Classic sign of vestibular disease? Which side is the lesion on?

A

Head tilt

Head tilt is towards lesion (because ipsilateral effect)

33
Q

Signs of vestibular disease

A

Nystagmus
Head Tilt
Leaning/Falling/

34
Q

How can you decide which side the vestibular system is damaged on, just based on nystagmus?

A

Vestibular system damaged on slower side of eye movement

35
Q

Describe cerebellar ataxia?

A

Not knowing where you are in space, exaggerated movements, wide base stance

36
Q

Describe vestibular ataxia

A

Head tilt with ataxia, horizontal eye movements, balance issues, falling to one side

37
Q

Describe spinal/ proprioceptive ataxia

A

Crossing over, feet tangled up, thoracic/pelvic limb moving at different paces