neurophysiology Flashcards
what is decussation?
axon of the 2nd order neuron crosses over to the opposite side of the CNS.
Pain signals are carried by _____ and _____fibres
A-delta
B- C
sensory neurons that bring pain sensations into the CNS release which neurotransmitters?
glutamate and/or substance P
name 3 disorders of pain sensations
allodynia
Hyperalgesia
hypoalgesia
allodynia
Pain due to a stimulus that does not normally provoke pain.
Hyperalgesia
Increased pain from a stimulus that normally provokes pain.
chemicals that stimulate pain receptors?
Bradykinin
5-HT serotonin
H+
ATP
Prostaglandin
Histamine
Substance P is release by sensory neuron to stimulate mast cells or neutophils to release HIstamine
Explain referred pain.
The localization of cutaneus sensation to a particular part of the body also dependes on the particular pathway it takes to the CNS. Pain arising in a visceral structure is percieved as coming from a portion of body surface, because developmentally related nerve fibers come from these anatomically different r
Pain management
(endogenous system)
the gate theory
descending pain inhibition pathways