neuronal communication Flashcards

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1
Q

describe the structure of a neurone

A

cell body (contains nucleus and other organelles)

dendrons (carry impulse towards cell body)

axons (carry impulse away from cell body)

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2
Q

What are three types of neurones

A

sensory

motor

relay

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3
Q

What do motor neurones do

A

involved in transmitting electrical
impulses from the CNS to effectors

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4
Q

What do sensory neurones do

A

transmit impulses from receptors to CNS

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5
Q

What do relay neurones do

A

located in the CNS and transmit impulses from sensory to motor neurones

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6
Q

describe the nature of neurones

A

polarised

at resting state outside of neurone is positive and inside is negative

this allows them to carry action potentials

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7
Q

how is speed of transmission increased

A

myelin sheath ( insulates axons)

formed by Schwann cells

mechanism that speeds transmission is known as saltatory conduction

action potential jumps between gaps of myelin sheath known as nodes of Ranvier

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8
Q

Why are neurones polarised

A

imbalance between sodium and potassium ions

potential difference across membrane with value of -70mv (resting potential)

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9
Q

How is resting potential maintained

A

sodium-potassium pumps move sodium ions out of neurone

creates electrochemical gradient as conc of Na is higher outside

membrane not permeable to Na so cannot enter

potassium pumps transport potassium into neurone but potassium diffuses back out due to potassium ion channels

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10
Q

describe stimulation of a neurone

A

excitation by stimulus causes sodium ion channels to open

makes neurone permeable to sodium ions so sodium ions diffuse into neurone down electrochemical gradient

makes inside less negative

when threshold is reached -55mv, more sodium channels open

giving p.d of 30mv ( end of depolarisation)

Repolarisation is achieved as a result of sodium ion channels closing and potassium channels opening

potassium ions diffuse out of neurone and eventually restore resting potential

closing of K channels is delayed so p.d becomes greater than resting

restored with sodium potassium pumps

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11
Q

What are synapses

A

junctions between two neurones

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12
Q

Explain what happens at the synapse

A

upon arrival of action potential

presynaptic membrane depolarises

causing ca channels to open

calcium ions enter neurone

fusion of synaptic vesicles and presynaptic membrane

neurotransmitter is released into synaptic cleft and diffuses through it

neurotransmitter binds to receptor in postsynaptic membrane

cation channels open

sodium ions enter

another action potential occurs

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13
Q

What are receptors

A

cells specialised for detection of stimuli

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14
Q

feature of receptors

A

transducers-convert wone form of energy into another

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15
Q

What are pacnian corpuscles

A

pressure receptors found in skin

convert mechanical energy to electrical energy

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16
Q

How do pacnian corpuscles work?

A

when it is squashed plasma membrane is deformed

makes membrane more permeable to sodium ions

depolarisation starts

17
Q

describe the structure of sensory neurones

A

Short dendrites

one long dendron

one short axon

18
Q

describe the structure of motor neurones

A

many short dendrites

one long axon

19
Q

Describe the structure of relay neurones

A

many short dendrites

many short axons

20
Q

How do neurotransmitters transmit nerve impulses between neurones

A

Action potential arrives at synaptic knob (of presynaptic neurone)

stimulates voltage gated calcium channels to open

This causes synaptic vesicle to move to presynaptic membrane

neurotransmitter diffuses across synaptic cleft and binds to receptors in post synaptic membrane

sodium channels open

depolarisation occurs

21
Q
A