Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Foundations of Neuroscience > Neuromuscular junction > Flashcards

Neuromuscular junction Flashcards

1
Q

What is a neuromuscular junction?

A

A specialised synapse between a motor neurone and muscle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How is different to a normal synapse?

A

The post synaptic cell is a muscle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does it trigger?

A

Muscle contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is it specialised to do?

A

Rapid reliable neurotransmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where does the motor neurone terminate?

A

At the motor end-plate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What specialisation can be seen at the post synaptic membrane?

A

Lots of folds

Meaning lots of receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What neurotransmitter is used?

A

Acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is synaptotagmin?

A

A sensor of Ca2+ levels
Triggers movement of vesicles
Vesicle fuses with membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What receptors are present in neuromuscular junctions?

A

Nicotinic acetylcholine receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What kind of channels are receptors?

A

Ligand-gated channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What happens after ACh binds to the ACh receptor?

A

The channel opens

It is permeable to Na+ and K+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the Em of the muscle cell?

A

-90mV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the ion movement in the cell?

A

More Na+ influx than there is K+ efflux

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe the driving force on Na+ and K+

A

Na+ is great

K+ is very small

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the end-plate potential?

A

-20mV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What determines end-plate potential?

A

-20mV is the potential after the release of neurotransmitter

17
Q

What does the end-plate potential initiate?

A

An action potential in the muscle

18
Q

What is the difference between the end-plate potential and the action potential?

A

The end-plate potential decays
Decreases as distance from motor end-plate increases
The action potential does not

19
Q

What is the delay between a presynaptic action potential and an end-plate potential?

A

1msec

20
Q

Comment on the size of an end-plate potential, why?

A

It is a very large synaptic potential
High density of receptors
Large release of neurotransmitter

Foundations of Neuroscience (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions