Chemical senses Flashcards

1
Q

What are the functions of chemical senses?

A

Finding food
Finding a mate
Avoiding dangerous substances
Homeostasis

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2
Q

What are the receptors of chemical senses?

A

Chemoreceptors

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3
Q

What are the human chemical senses?

A

Taste (gustation)

Smell (olfaction)

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4
Q

What are the 5 basic tastes?

A
Salt
Sour
Sweet
Bitter
Umami
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5
Q

Where are the taste cells?

A

Tongue
Palate
Pharynx

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6
Q

What is the structural organisation of taste cells?

A
Papilla
Taste buds
Pore
Basal cells
Taste cells
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7
Q

What is the lifespan of taste receptor cells?

A

2 weeks

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8
Q

What are the stages from stimulus to action potential in a taste cell?

A
Chemical behinds
Receptor potential
Depolarisation
Voltage gated Ca2+
Calcium entry
Neurotransmitter released
Excites sensory neurone
Action potential
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9
Q

How is salt detected?

A

Sodium entry via non-gated channels

Results in depolarisation

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10
Q

How are sour tastes detected?

A

H+ entry via TRP
Blocks the K+ channel
Results in depolarisation

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11
Q

How are sweet, umami, bitter tastes detected ?

A

G protein coupled receptors

T1R and T2R families

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12
Q

Which nerves transmit taste?

A

VII
IX
X

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13
Q

Where does the signal go after the cranial nerves?

A

To the gustatory nucleus

Then the gustatory cortex

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14
Q

What is ageusia?

A

Inability to taste

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15
Q

What is neural coding of taste?

A

Comparing all pathways

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16
Q

What are the secondary pathways of taste?

A

Swallowing and salivation

17
Q

What is more sensitive taste or smell?

A

Smell

18
Q

What is the combination of taste and smell?

A

Flavour

19
Q

Where are smell receptors?

A

Olfactory epithelium

20
Q

Describe olfactory cells?

A

Olfactory cells are neurones
Replaced every 4-8 weeks
Each cell is one type of receptor molecule
Each receptor molecule binds a range of odorants

21
Q

What is population coding?

A

Co-ordinated firing of multiple neurones

22
Q

How are action potentials triggered in olfactory cells?

A
Odorant binds to receptor
G protein mediated events
Intracellular cascade
Na+/Ca2+ channels open
Depolarisation
Receptor potential
Action potential
23
Q

Which cranial nerve carries olfactory signals?

A

I

24
Q

What is the olfactory pathway?

A

Olfactory neurons
Olfactory bulb
Olfactory cortex
Recognition/association in the orbitofrontal cortex