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Ch. 8 - Neurology > Neuromuscular Disorders > Flashcards

Neuromuscular Disorders Flashcards

1
Q
A
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2
Q

Define the term neuromuscular disorders.

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3
Q

What is the mean age of onset of neuromuscular disorders?

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4
Q

What are the RFS for the development of neuromuscular disorders.

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5
Q

Describe the pathophysiology of neuromuscular disorders.

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6
Q

List the 4 types of neuromuscular disorders? which is the most common?

A
  1. Amyotrophic Lateral Sclerosis - most common
  2. Progressive Bulbar Palsy
  3. Progressive Muscular Atrophy
  4. Primary Lateral Sclerosis
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7
Q

Describe the features of ALS.

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8
Q

Describe the features of progressive bulbar palsy.

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9
Q

Describe the features of progressive muscular atrophy.

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10
Q

Describe the features of primary lateral sclerosis.

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11
Q

Symptoms of neuromuscular disorders can be separated into UMN, LMN, pseudobulbar, bulbar and respiratory symptoms.
What are the UMN symptoms?

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12
Q

Symptoms of neuromuscular disorders can be separated into UMN, general LMN, pseudobulbar, bulbar and respiratory symptoms.
What are the general LMN symptoms (not including the pseudobulbar/bulbar palsy symptoms)?

A
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13
Q

Symptoms of neuromuscular disorders can be separated into UMN, LMN, pseudobulbar, bulbar and respiratory symptoms.
What are the pseudobulbar symptoms?

A
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14
Q

Symptoms of neuromuscular disorders can be separated into UMN, LMN, pseudobulbar, bulbar and respiratory symptoms.
What are the bulbar symptoms?

A
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15
Q

Symptoms of neuromuscular disorders can be separated into UMN, LMN, pseudobulbar, bulbar and respiratory symptoms.
What are the respiratory symptoms?

A
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16
Q

List the symptoms of neuromuscular disorders.

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17
Q
A
18
Q

Where does UMN become LMN?

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19
Q

What is the pathophysiology behind dysphagia in a UMN vs LMN lesion?

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20
Q

What is the pathophysiology behind uncoordinated movements in a UMN vs LMN lesion?

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21
Q

What is the pathophysiology behind falls in a UMN vs LMN lesion?

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22
Q

Are spasms UMN, LMN or both?

A
23
Q

You are asked to perform a focused exam on a patient with a neuromuscular disorder. What exams will you do? What would you expect on general inspection?

A

you would also offer speech and swallow assessment

24
Q

What cranial nerves are mostly affected by neuromuscular disorders?

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25
Q

You are asked to perform a focused exam on a patient with a neuromuscular disorder. What would you expect on cranial nerve exam?

A
26
Q

You are asked to perform a focused exam on a patient with a neuromuscular disorder. What would you expect on motor exam?

A

weakness - decreased power and coordination.

+ gait - unsteady/ spastic gait vs flaccid gait

27
Q

You are asked to perform a focused exam on a patient with a neuromuscular disorder. What would you expect on sensory exam?

A
28
Q

List the ddx for neuromuscular disorders and state the differentiating features.

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29
Q

How would you diagnose a neuromuscular disorder?

A

IT IS A Dx OF EXCLUSION!!

30
Q

List and justify the investigations you would order for a suspected neuromuscular disorder and state your expected findings.

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31
Q

The management of a patient with neuromuscular disorders require MDT input. Who would be involved in the MDT and what are their roles?

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32
Q

What is the disease - modifying drug used in the treatment of neuromuscular disorders? What is the MOA and the SEs? How is the drug monitored?

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33
Q

Outline the pharmacological management of neuromuscular disorders.

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34
Q

Outline the adjunctive/ surgical management of neuromuscular disorders.

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35
Q

What are the complications of neuromuscular disorders?

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36
Q

What is the average lifespan of a patient with neuromuscular disorders from dx?
What are 2 good and 1 poor prognostic factor of neuromuscular disorders?

A

Ch. 8 - Neurology (10 decks)

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