Neuromuscular Blockers

Question 1

What is an example of a muscle nAChR agonist that depolarizes?

Answer 1

SUCCINYLCHOLINE: this drug works to over stimulate the nAChR which will cause desensitization of the receptor.
It causes paralysis

Question 2

What is an example of a muscle nAChR antagonist that depolarizes the NMJ?

Answer 2

ATRACURIUM: This drug works by competing with ACh for binding at the receptor. At high enough concentrations it prevents ACh from binding completely so you see paralysis