Neuromuscular Blockers Flashcards
1
Q
Succinylcholine
A
Concentration: 20 mg/ml Mechanism of Action: ACh Agonist (Depolarizing NMB) Intubating dose: 1-1.5mg/kg Mx dose: Onset: 30-60 sec Peak: 60 sec Duration: 4-6 min T1/2B: 1 min Elimination: Plasma Cholinesterases
2
Q
Rocuronium
A
Concentration: 10 mg/ml Mechanism of Action: Nicotinic M Antagonist (Nn presynaptic); NDNMB Intubating dose: 0.6-1.2 mg/kg Mx dose: 0.15 mg/kg Onset: 60-120 sec Peak: 1-3 min Duration: 30-85 min T1/2B: 1.4 hours Elimination: Renal/Hep
3
Q
Vecuronium
A
Concentration: 1 mg/ml Mechanism of Action: Nicotinic M Antagonist (Nn presynaptic); NDNMB Intubating dose: 0.1 mg/kg Mx dose: 0.05 mg/kg Onset: 2-3 min Peak: 3-5 min Duration: 30 min T1/2B: 1-1.25 hours Elimination: Renal/Hep
4
Q
Cisatracurium
A
Concentration: 2 mg/ml Mechanism of Action: Nicotinic M Antagonist (Nn presynaptic); NDNMB Intubating dose: 0.1 - 0.2 mg/kg Mx dose: 0.02 mg/kg Onset: 2-3 min Peak: 3-5 min Duration: 30 min T1/2B: 30 min Elimination: Hoffman (pH and temp dependent)
