IV Induction Agents Flashcards
1
Q
Propofol
A
Concentration: 10mg/ml Mechanism of Action: GABA Agonist Dose: 2-2.5 mg/kg Onset: 30-40 sec Peak: 60 sec Duration: 4-8 min T1/2B: 1-3 hours Elimination: Hep/Pulm
2
Q
Etomidate
A
Concentration: 2mg/ml Mechanism of Action: GABA Agonist Dose: 0.2-0.3 mg/kg Onset: 30-60 sec Peak: 60 sec Duration: 4-8 min T1/2B: 3 hours Elimination: Hep/Plasma cholinesterase
3
Q
Ketamine
A
Concentration: 50mg/ml Mechanism of Action: NMDA Antagonist Dose: 1-2 mg/kg Onset: 30-60 sec Peak: 60 sec Duration: 5-10 min T1/2B: 3 hours Elimination: Hep
4
Q
Midazolam
A
Concentration: 1 or 5 mg/ml Mechanism of Action: BZ Agonist on GABA Dose: 0.15-0.35 mg/kg; 1-5mg for sedation Onset: 30-120 sec Peak: 3-5 min Duration: 15-80 min T1/2B: 1.5-3.5 hours Elimination: Hep
5
Q
Thiopental
A
Concentration: 25mg/ml Mechanism of Action: GABA Agonist Dose: 3-5 mg/kg Onset: 30-40 sec Peak: 30-60 sec Duration: 5-8 min T1/2B: 12 hours Elimination: Hepatic
6
Q
Dexmedetomidine
A
Concentration: 100mcg/ml Mechanism of Action: Alpha 2 agonist Load dose: 1mcg/kg over 10 min Mx dose: 0.2-0.7 mcg/kg Onset: 10-15 min Peak: Infusion Duration: 4 hours T1/2B: 2 hours Elimination: Hep
