Local Anesthetics Flashcards
1
Q
Lidocaine
A
Mechanism of Action: Amide Na Channel blocker Onset: Rapid-Mod Duration Spinal: 60-70 min Duration Epidural: 60-120 min Max Dose: 350 mg; 500mg w/ epi Plain: 4.5 mg/kg With epi: 7 mg/kg pKa: 7.9 Elimination: Hep
2
Q
Bupivicaine
A
Mechanism of Action: Amide Na Channel blocker Onset: Moderate Duration Spinal: 2-3 hours Duration Epidural: 120-200 min Max Dose: 175-225 mg Plain: 2.5 mg/kg With epi: 3 mg/kg pKa: 8.1 Elimination: Hep
3
Q
Ropivicaine
A
Mechanism of Action: Amide Na Channel blocker Onset: Moderate Duration Spinal: 2-3.5 hours Duration Epidural: 120-180 Max Dose: 200 mg; 250 mg w/ epi Plain: 3 mg/kg With epi: 3 mg/kg pKa: 8.1 Elimination: Hep
