Neurology Flashcards
ACA embolism
Feet and leg deficits
MCA embolism
Hands, Arms, Face, Speech deficits
PCA embolism
Visual Cortex deficits
Cerebellar embolism
Coordination deficits (Ataxia)
Stroke Presentation
Focal neurologic deficit localized to the brain
Stroke Diagnostic steps
- Non-Con CT head
negative blood-Ischemic Stroke
Positive blood-Hemorrhagic stroke
Ischemic Stroke Diagnostic Steps
give tPA maybe
next day do 2d echo
EKG
Carotid U/S
Hemorrhagic stroke treatment
Decrease Blood pressure
neurosurgery
2D echo shows thrombus
Warfarin
Noac
Heparin bridge
EKG shows A-fib/flutter stroke
Warfarin
Noac
Carotid artery Stenosis Treatment
<70% occlusion + Asx
>70% + Sx or >80% occlusion
Surgery within two weeks
Contraindications to tPA
Bleeding
Recent surgery within 2 weeks
ICH
When to use tPA
<3hr BP-180/105
<4.5 DM BP-180/105
Causes of 1st time seizure
VITAMIN
Vascular Infection Trauma Autoimmune Metabolic Ingestion/wIthdrawl Neoplasm pSych
Seizures Presentation
Loss of consciousness, Jerking
Bowel/Bladder incontinence
Tongue Biting
Post ictal state
Seizure no epilepsy (1st time)
Currently seizing, (>5m or failure to return to baseline after >20 min) Benzos Fosphenytoin Midozolam + propofol Phenobarbital
Seizure with h/o of epilepsy
Check medication levels
increase drug dose
Add drug
change drug
General Seizure coverage
Valproate, Lamotrigine, Levatiracetam
Atonic seizure presentation treatment
No LOC, (+) LOT, Suddenly fall
Valproic acid, valproate
Myoclonic Presentation, Treatment
No LOC, too much tone
Valproic acid, Valproate
Trigeminal Neuralgia Treatment
Carbamazepine
Parkinsons Presentation
Bradykinesia
Cogwheel Rigidity
Resting tremor (Pill rolling)
Gait/postural instability-Shuffling steps
Parkinsons treatment <70, good function
dopamine agonists
Ropinerol, Promipexole
Parkinsons treatment >70 with decline in function
levodopa + carbidopa
Essential tremor presentation
tremor with movement or use, no tremor at rest
Tx: Propanolol
Intention tremor Presentation
cerebellar dysfunction
alcohol stroke
tremor with movement none at rest
worsens closer to the target
Tension headache Presentation, Treatment
Most common
Muscular pain, Bilateral
Starts in front and radiates to the neck
Tx: NSAIDs
Analgesic Rebound Presentation, treatment
Withdrawl
Pt: Takes medication more than 10x/month
HA when they stop their meds
Tx: Let them withdraw
Cluster Headache Presentation, treatment
Asx for months then happens 8-10x/day unilateral pain with Horner Syndrome Tx: Acute-O2 Sumitriptan ppx-CCB (verapamil) f/u with MRI
Migraine presentation, treatment
unilateral pulsatile, debilitating HA, photphobia, phonophobia, N/V, aura, trigger Tx: Acute, Mild-NSAIDs Mod/severe-Triptans ppx-b-blockers Valproate topiramate
Migraine Prophylaxis
B-blockers
Valproate
Topiramate
Cluster Headache Prophylaxis
CCB=Verapamil
Idiopathic Intracranial Hemorrhage Presentation, treatment
Woman, increased ICP, Papilledema, N/V, FND, negative CT, OCP use Dx: LP, OP >25 Tx: Acetazolamide Serial LP VP shunt
Musculoskeletal pain Presentation, Tx
Vague symptoms 30-50 y/o h/o heavy lifting Tx: Exercise and NSAIDs reassess after 4 weeks
Disc Herniation Presentation, Dx, Tx
Sciatica pain Positive Straight Leg test 30-50 heavy lifting Dx: X-ray MRI Tx: NS > conservative @ 6mo NS=conservative @ 1 year
Compression Fracture presentation, Dx, Tx
>50 F Fall on coccyx (+) vertebral step off (+) pinpoint tenderness Dx: X-ray best MRI Tx: Surgery
Spinal Stenosis Presentation, Dx, Tx
Narrow Canal >50 Pseudoclaudication positional, Hunched over Dx: x-ray MRI Tx: Laminectomy
Osteophyte (bone spur) Presentation, Dx, Tx
>50 No heavy lifting Sciatica positive straight leg raise Dx: X-ray MRI Tx: Surgery
Alarm symptoms for lower back pain
bowel/Bladder incontinence
Saddle Anesthesia
New FND/rapidly progressing
Alzheimers Presentation, Dx, Tx
Associated with downs Memory goes first Down syndrome spares social graces Dx: CT=diffuse cortical atrophy Tx: Supportive care Family education Donepezil
Creutz-feld Jakob Presentation, Dx, Tx
Undercooked meat, Sporadic mutation
young dementia with myoclonus
Dx: MRI
Tx: Supportive
Normal Pressure Hydrocephalus Presentation, Dx, Tx
Increased ICP Pt: Wet, Wobbly, Weird Dx: CT- Hydrocephalus LP- will provide improvement Tx: VP Shunt
Neiman Picks disease Presentation, Tx
Personality goes 1st, Hypersexual
Tx: Supportive
Vascular Dementia presentation, Dx, Tx
Stepwise decline with each stroke
Dx: Ct=infarcts
Tx: CVA, supportive
Lewey-Body Dementia Presentation, Tx, Dx
Parkinsonian Sx and dementia
Visual Hallucinations
Tx: Supportive
Vertigo
(-) tinnitus, hearing loss
(+) FND
Posterior Fossa insult
MRI
Posterior Fossa Insult Presentation, Dx, Tx
MS, Stroke, Tumor, Abscess, Seizure, Migraine FND (-) ear Sx Dx: MRI Tx: Disease Specific
BPPV presentation, Dx, Tx
Reccurrent and reproducible vertigo
lasts <1 min
Dx: Dix Hallpike (Rotary Nystagmus)
Tx: Epley Maneuver
Menier’s Disease Presentation, Dx, Tx
Hearing loss, tinnitus, Vertigo Lasts >30m <1hr Tx: Salt restriction Thiazide diuretics Meclizine
Vestibular Neuritis Labrynthitis Presentation, Tx
4 wks after URI Vertigo 1-10m (+) Hearing loss N/V Tx: Steroids Meclozine
Multiple Sclerosis Presentation, Dx
AI, Demyelinating 20-40 Any neuro Sx separated by time and space Optic neuritis Dx: MRI=periventricular white matter
Multiple Sclerosis Tx
Acute Flare=Steroids
Chronic= Interferon
Glatramer
Finoglonad
Multiple Sclerosis Complications and treatment
Urinary retention=bethanachol
Urinary incontinence=Amitryptiline
Spasms=Baclofen
Neuropathic pain=Gabapentin
ALS presentation, Dx, Tx
UMN and LMN lesions
Dx: EMG
Tx: Supportive
Guillain Barre Syndrome Presentation, Dx, Tx
Watery diarrhea or presenting after a flu shot Ascending paralysis, Distal to proximal Hyporeflexia Dx: LP=alot of proteins few cells Tx: Intubation IVIg=plasmapheresis NEVER STEROIDS
Myasthenia Gravis Presentation, Dx, Tx
>50 Fatigue of the eyes, throat, fine movements Worse in the evening Dx: Abs against AChR EMG CT scan for thymoma (assoc) Tx: Cholinesterasei(Stigmine) Steroids refractory IVIg=plasmapheresis Crisis
Eaton Lambert Presentation, Dx, Tx
Presynaptic CaR Paraneoplastic Syndrome >50 Improvement w/use Proximal muscles-problems combing hair, rising out of a chair Dx: Abs EMG CT Small cell Tx: Treat CA