Neurology Flashcards
When to initiate Aspirin in acute stroke?
Within 48 hrs, not within 24 hrs of thrombolysis
Timeframe for use of tPA?
4.5 hours
Absolute exclusion criteria for thrombolysis?
Uncertainty about timeframe
INR>1.7 or anticoagulant in last 12 hours
SAH
Septic embolus
Hypo/hyperglycaemia which cannot be corrected in 4.5hrs
Example of tPA?
Alteplase
Last resort for huge MCA stroke?
Hemicraniectomy
Presentation of amyloid angiopathy
Recurrent cortical, lobar strokes, or SAH
Investigations in stroke workup?
CT, CTA/MRI/MRA, carotid duplex, ECG, holter monitor, TOE, BGL, lipids, CBE, LFT
Secondary prevention of stroke?
Aspirin
Dipyridamole (ER)
Warfarin/NOACs for cardioembolic
Carotid endarterectomy
BIGGEST risk factor for ischaemic stroke?
Hypertension
smoking/Obesity second
BIGGEST risk factor for haemorrhagic stroke?
Hypertension
Obesity/physical inactivity second