Gastroenterology Flashcards
Drugs used for IBD management?
Sulfasalazine (5-ASA)
Corticosteroids for flare-ups
Azathioprine
Infliximab (TNF-a inhibitor)
Side effect of Sulfasalazine?
Infertility in males (reversible)
Hepatic condition assoc. with UC?
PSC
What indicates successful hepatitis B vaccination?
HbsAb
Testing for coeliac disease?
Serological: Anti-TTG, Anti-endomyseal
Jejunal biopsy is definitive - villous atrophy, crypt hyperplasia.
BUT make sure they have been eating gluten for at least 6 weeks prior to either of these investigations.
Foods to be avoided in Coeliac Disease
BROW Barley Rye Oats Wheat
Sinister differential for a woman over 50 with IBS symptoms?
Ovarian cancer
DIagnostic test in Wilson’s disease?
Reduced Caeruloplasmin
Increased 24hr urinary copper excretion
Urgent indications for endoscopy?
Dysphagia
Upper abdo mass
Weight loss+reflux/abdo pain
Management of reflux with no indications for endoscopy?
Review meds for potential cause
lifestyle advice (w. loss, reduce big meals before bed/supine)
Trial of PPI
H.Pylori testing
HbeAg purpose?
Marker of infectivity; released from infected hepatocytes
Mx of C.diff infection?
Stop offending antibiotic, start metronidazole
Immediate Mx of Varices
ABCDE Correct clotting abnormality (FFP,pro,vit.K) Terlipressin/Octreotide Endoscopic band ligation TIPS if all else fails
Prevention of Varices?
Propranolol
Ligation