Neurology Flashcards
Which is the more common etiology of stroke?
Thromboembolic
What is the time window for TPA in an embolic stroke?
Ideally within 3 hours but demonstrates effectiveness up to 4.5 hours fro onset of symtoms
What is the threshold for carotid endarterectomy?
> 70% occlusion of the carotid
If a patient has a TIA, what are his/her risk of CVA?
33% in 5 years
How long must a seizure persist to be diagnosed as having status epilepticus?
5 minutes
What is the treatment for MS?
Acute: high dose IV steroids -> plasma exchange if that doesn’t work. Chronic - interferon beta decreases the frequency of acute events especially in more severe cases. Glatiramer acetate is used in more mild cases.
What is the risk of alzheimer’s disease by age 85?
30-50%
What is the standard treatment of alzheimer’s disease?
Acetylcholinesterase inhibitor (tacrine, donepezil, galantamine or rivastigmine) + Memantine
A patient with a chronic evolution of apathy and ALS receives a PET scan which shows frontal hypometabolism. What is the diagnosis?
frontotemporal dementia
What are the treatments/preventions of headache?
Triptans, botox for severe intractable headache
What is the prophylactic medication of choice for cluster headaches?
Verapamil
What are the 4 main clinical diagnostic criteria for Parkinson’s disease?
Resting tremor, bradykinesia, rigidity, postural instability
What is the next medication step for a Parkinson’s patient who fails levadopa/carbidopa therapy?
bromocriptine
What is the chromosomal location of the Huntington’s gene?
short arm of chromosome 4
What is an important supplement to ropinerole in restless leg syndrome?
Iron