Neurology Flashcards
By age 18 mo what gross motor action occurs?
walking up stairs
By age 24 mo what gross motor action occurs?
Running
By age 12 mo what gross motor action occurs?
walks w/ one hand held
By age 9 mo what gross motor action occurs?
pulls themselves up to stand
By age 6 mo what gross motor action occurs?
Sits momentarily
By age 3 mo what gross motor action occurs?
Supports weight on forearms
What fine motor skill is present at 3 mo?
Opens hands spontaneously
What fine motor skill occurs at 6 mo?
Transfer of objects between hands
What fine motor skill occurs at 9 mo?
Pincer grasp
What fine motor skill occurs at 12 mo?
Releases object on command
What fine motor skill occurs at 18 mo?
Feeds from a spoon
What social skill appears at 3 mo?
Smiles appropriately
What social skill occurs at 6 mo?
shows likes/dislikes
What social skill appears at 9 mo?
Plays patty-cake
What social skill appears at 12 mo?
Comes when called
What social skill appears at 18 mo?
Mimics actions
What social skill appears at 24 mo?
Plays with others
What language skill appears at 3 mo?
Coos & Laughs
What language skill appears at 6 mo?
Babbles
What language skill appears at 9 mo?
Imitates sounds
What language skill appears at 12 mo?
1-2 meaningful words
What language skill appears at 18 mo?
Knows at least 6 words
What language skill appears at 24 mo?
2-3 word sentences
2 at 2 yo; 3 at 3 yo; 4 at 4 yo
Craniotabes is a sign of what?
Prematurity
Bulging fontanelles is a sign of what?
Increased ICP
Loud bruits are seen in which pediatric conditions?
- Increased ICP
- Severe anemia
- AV malformations
Soft bruits may be normal at what age?
< 4 yo
Gower’s sign is a sign of?
Pelvic girdle weakness
A positive romberg sign is seen with what type of sensory disorder?
Sensory ataxia
Ansomia is noted in what disorders?
- Zinc deficiency
- Kallmann’s syndrome
Papilledema is a sign of?
Increased ICP
S/Sx of Horner’s Syndrome.
- Damage to SANS nerves on side of neck
- Contracted pupils
- Drooping upper eyelid
- Local inability to sweat on one side
Medial deviation of pupils denotes what nerve?
Abducens (CN VI)
Up & Out deviation of pupils denotes what nerve?
Trochlear (CN IV)
Down & Out deviation of pupils denotes what nerve?
Oculomotor (CN III)
Horizontal nystagmus denotes what type of injury?
Labyrinth or vestibular injury
Vertical nystagmus denotes what type of injury?
Brain stem
Argyll-Robinson pupils are a sign of what disorder(s)?
- Neurosyphilis
- Diabetes
Fixed dilated pupils appear on what condition?
Brain death
What are Argyll-Robinson pupils?
Constrict on near objects but not with light
Mydriasis can be indicative of?
- SANS overactivity
- Hyperthyroidism
- Anxiety
Miosis can be indicative of?
- PANS
- Morphine overdose
- Neurosphilis
The Accessory nerve affects what muscles?
- SCM
- Trapezius
The hypoglossal nerve affects what muscles?
Tongue
What is the taste innervation of the glossopharyngeal nerve (CN IX)?
Posterior 1/3 of tongue
Vagus N disruption can lead to what?
Paralysis of vocal cords & soft palate
Explain caloric testing of vestibular function?
COWS
* Cold –> opposite
* Warm –> same
What is the taste innervation of the facial N (CN VII)?
Anterior 2/3 of tongue
Detail an UMN CN VII problem.
- involves only lower part of face on the opposite side
- Angle of mouth drops, cheeks puff loosely, can wrinkle forehead and say yes
Detail LMN CN VII lesion.
- Whole face is involved
Bell’s Palsy; Ramsay-Hutn Syndrome
Epilepsy is defined as?
Recurrent seizures unrelated to fever or acute brain insult (trauma)
How can you say a patient has had a definite seizure?
Altered EEG activity & LOC
40% of childhood seizures are of what type?
Partial
What type of seizure notes that only part of the body is involved and no LOC occurs?
Simple partial seizures
What does the EEG show during partial simple seizure?
Spikes/waves
Compare a simple partial seizure with a complex partial seizure.
Simple: part of body; no LOC
Complex: simple partial seizure + LOC; 30% have aura
What lobe may be lesioned if a patient suffers from complex partial seizures?
Temporal
What is the presentation of absence seizures?
- Body goes “limp” w/ NO jerking
- Blank facial expression with eyelid flickering
- No aura or post-ictal phase
- May occur due to hyperventilation
What may facilitate absence seizure occurence?
Hyperventilation
What does the EEG show during an absence seizure?
3 sec spike & wave discharge
Explain the presentation of generalized tonic-clonic seizures.
- Aura w/ post-ictal phase
- loss of bladder control
- Vomitting and HA after seizure
- Precipitated by fever & certain medications
Detail, very basically, a myoclonic seizure.
Symmetric muscle contractions w/ loss of body tone
Detail infantile spasms.
- 4-8 mo
- Symmetric contractions of head/neck/trunk/extremities
- 3 types: flexor, extensor, mixed
What is the EEG pattern of infantile spasms?
Hypsarrhtyhmia pattern
When do febrile seizures peak?
9 mo to 5 yo (peak at 14-18 mo)
T/F: there is a strong FMH of febrile seizures
True
Febrile seizures must be associated with what?
Fever
Many patients who have had a seizure will display what metabolic abnormality post-ictal?
Hypoglycemia
What is the Tx of absence seizures?
Ethosuximide
What ist he Tx of infantile spasms?
ACTH
can get Cushing’s syndrome
How long does medication therapy continue for epilepsy?
- Must be seizure free ≥2 years
- Gradual withdrawal over 3-6 months
What vessel markers are used regarding the prognosis of skull fractures?
- Meningeal vessels
- Sagittal sinus
- Lambdoid suture
What is a complication of skull fractures?
Leptomeningeal cyst
* meninges herniate between bones of fracture
* Bones cannot form together and heal
What type of fracture gives a Raccoon eye appearance?
Basilar skull fracture
Otorrhea & Rhinorrhea
What is the limit used to determine whether a skull fracture (depressed) needs surgical correction?
> 3-5 mm
How many people with a concussion experience LOC?
10%
What are S/Sx of a concussion?
- Decreased mental status
- Persistent confusion
- Excessive vomiting
- Unreliable Hx
- Focal neurological exam
- Seizures
- Skull fracture
A subdural hematoma is a sign of what type of abuse?
Shaken Baby syndrome
A battle sign describes what feature of a subdural hematoma?
Ecchymosis behind ear
What is the Tx of Cerebral edema?
- Usually causes death
- Elevate head to 30°
- Hyperventilate: PCO2 = 30-35 mmHg
- Mannitol 20% IV @ 1-1.5 g/kg
What are S/Sx of epidural hematoma?
- Bleeding in extradural space
- Rupture of middle meningeal artery
- Brief LOC then lucid that relapses
What are S/Sx of subdural hematoma?
- Vomiting
- Irritability
- Shrill cry
- HA
- Bulging fontanelle
- Setting Sun eyes
- Retinal hemorrhages
- Battle sign