Neurology Flashcards
With damage to the thoracic vertebrae on the right side what sensation will be lost in the left leg?
- Temperature
- Pain
- Crude touch
With damage to the thoracic vertebrae on the right side what sensation will be lost in the right leg?
- fine touch
- vibration
- proprioception
What are the features of lateral medullary syndrome?
Ataxia Dysarthria Dysphagia Ipsilateral Horners ipsilateral pain and temp loss on face contralateral pain and temp loss in body
What are the neurological presentation of basilar artery occlusion?
1) Locked in syndrome
- quadriparesis
- preserved consciousness and ocular movements
2) sudden death
3) loss of consciousness
What artery is involved in lateral medullary syndrome?
right or left posterior inferior cerebellar artery (artery is on same side as symptoms in face)
What artery will cause lateral pontine syndrome?
anterior inferior cerebellar artery
How are haemorrhage strokes treated?
- no aspirin or thrombolysis
- neurosurgical and neuropathy-critical care evaluation
- protect airway
- admit to neurology ICU
What is the treatment for ischaemic stokes?
- Aspirin 300mg orally
- IV alteplase (for thrombolysis providing within 4.5hr of onset)
How long after stroke onset is thrombolysis still first line management?
4.5 hours
Which stroke patients will receive thrombolysis?
- onset within 4.5 hours
- confirmed to not be hameorrhagic with imaging
When should a BP lowering medication be given to patients with haemorrhage stroke?
Only if BP greater than 140 systolic (as lowering BP can worsen cerebral perfusion)
What is the first line long term pharmacological therapy for stroke?
clopidogrel 75mg once daily + statin (e.g. Atrovastatin 80 mg once daily)
What are the risk factors for TIA?
- A-fib
- previous CV problems
- alcohol
- Migraines
- hyperlipideamia
- Diabetes
What are sulfonylurea drugs a risk factor for?
hypoglycaemia
How does bleeding present on CT?
Hyper-density
How is an extradural haemotoma likely to present?
- trauma
- loss of consciousness
- often have lucid interval between loss of consciousness
- deterioration common after lucid interval
How does a extradural haemotoma present on CT?
lentiform shaped heterogeneous hyper dense extra axial collection adjacent to left squamous temporal bone
How will subdural haematomas usually present?
- elderly patients
- on anticoagulants
- sub-acute confusion
- neurological deficit
- after minor fall
How does sub-arachnoid haemorrhage present?
- thunderclap headache
- photophobia
- meningism (+ neck stiffness)
How would ischaemic stoke show on CT?
cortical hypo-density associated with loss of grey white matter differentiation in vascular territory
What does smudge cells on a blood film indicate?
chronic lymphocytic leukaemia
What is the diagnostic test for leukaemia?
bone marrow biopsy and immune-phenotyping
What is first line diagnostic testing for pancytopenia?
1) blood film
2) bone marrow profile
What is treatment for patients in T2 respiratory failure?
(low O2 high CO2)
- non-invasive ventilation
- doxapram last line
What are the subunits of the mediastinum?
- superior mediastinum (first rib > T4)
- anterior mediastinum (T4 > T9, Sternum > ant pericardium)
- posterior mediastinum (T4 > T12, post pericardium > spine)
- middle mediastinum (T4-9, Lateral border = either side pericardium)
What blood cells are most likely to be raised in bacterial infection?
neutrophils
What blood cells are most likely to be raised in viral infection?
Lymphocyte
What blood cells are most likely to be raised in fungal infection?
eosinophil
What blood cells are most likely to be raised in protozoan infection?
monocyte
What are the gram positive cocci?
staphylococci
streptococci (inc enterococci)