Neurology Flashcards
1
Q
What causes SMA?
A
Alterations in snRNP, causing low in SMN protein (anterior horn cell degeneration)
2
Q
What are the causes of Alzheimer disease?
A
Sporadic: alteresd ApoE protein
Familial: altered APP, presenilin- 1, presenilin -2 protein
3
Q
Subfalcine herniation. Consequences? (1)
A
Cingulate gyrus herniate under falc cerebri. ACA compression
4
Q
Central/Downward transtentorial herniation. Consequences? (2)
A
brainstem caudal displaced. paramedian pontine artery rupture
5
Q
Uncal transtentorial herniation. Consequences? (2)
A
early: ipsi blown pupil, C/L hemiparesis
late: opposite side of above (kernohan phenomenon)
6
Q
Cerebellar tonsillar herniation. Consequences? (1)
A
thru the foramen magnum
coma and death