Neurology Flashcards

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1
Q

What causes SMA?

A

Alterations in snRNP, causing low in SMN protein (anterior horn cell degeneration)

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2
Q

What are the causes of Alzheimer disease?

A

Sporadic: alteresd ApoE protein
Familial: altered APP, presenilin- 1, presenilin -2 protein

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3
Q

Subfalcine herniation. Consequences? (1)

A

Cingulate gyrus herniate under falc cerebri. ACA compression

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4
Q

Central/Downward transtentorial herniation. Consequences? (2)

A

brainstem caudal displaced. paramedian pontine artery rupture

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5
Q

Uncal transtentorial herniation. Consequences? (2)

A

early: ipsi blown pupil, C/L hemiparesis
late: opposite side of above (kernohan phenomenon)

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6
Q

Cerebellar tonsillar herniation. Consequences? (1)

A

thru the foramen magnum

coma and death

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