Fungi Flashcards
1
Q
Histoplasmosis:
- Endemic area?
- Features: (5)
- Sx:
A
- Endemic area: southwest (Mississippi, Ohio river)
- Features: hides in macrophages, assoc with bird, bat dropping, dimorphic, cause pneumonia, can form granuloma but cant transmit person to person
- Sx: miSSissiPPi
skin (erythema nodosum), splenomegaly, palate/tongue ulcers, pancytopenia)
2
Q
Blastomycosis
- Endemic area?
- Features: (4)
- Sx:
A
- Endemic area: central, east (Great Lake)
- Features: buds broadly, dimorphic, cause pneumonia, can form granuloma but cant transmit person to person
- Sx: bone, skin (verrucous)
3
Q
Coccidioidomycosis
- Endemic area?
- Features: (3)
- Sx:
A
- Endemic area: east (California)
- Features: NON-dimorphic (spherules), cause pneumonia, can form granuloma but cant transmit person to person
- Sx: Jilat My Sexy Boner in California
joint, meningitis, skin (erythema nodosum/multiforme), bone
4
Q
ParaCoccidioidomycosis
- Endemic area?
- Features: (4)
- Sx:
A
- Latin america
- Captain wheel, dimorphic, cause pneumonia, can form granuloma but cant transmit person to person
- same with blastomycosis
bone, skin (verrucous), lung
5
Q
Aspergillus
- Morphology
- Affected areas:
- Treatment
A
- budding yeast with pseudohyphae at 20 degree C, germ tubes at 37 deg C, 45 degree angle branching septate hyphae with fruiting bodies
- ABPA, pneumonia (cavitation with fungus balls)
- Echinocandins (caspofungin)
6
Q
Candida
- Morphology
- Treatment
A
- budding yeast with pseudohyphae at 20 degree C
- Nystatin: oral, vaginal
Caspofungins: esophagitis
7
Q
Name fungi with pseudohyphae
A
aspergillus, candida
8
Q
Cryptococcus
- Morphology in various test
- Culture agar
- Tx
A
- yeast
- Indian ink: soap bubble appearance
- Mucicarmine: polysaccharide capsules stained red
- Latex agglutination test: agglutination present (most specific)
- culture in Saboraud agar
- tx: amphotericin B + flucytosine
9
Q
Mucormycosis
- Morphology
- Presentation
- Ppl at risk
A
- non septate hyphae that branch at right angle
- black eschar, penetrate cribriform plate (sinusitis, orbital cellulites, frontal abscess)
- DKA, immunosuppression