Neurodevelopmental Disorders Flashcards
1
Q
IDD criteria
A
- Low IQ (<70)
- Low adaptive skills
- Onset = developmental period
2
Q
IDD severity specifier
A
- Mild, Moderate, Severe, Profound
- Based on adaptive skills
3
Q
IDD etiology
A
- Most prenatal = Down’s, Fragile X, FAS
- Some perinatal = asphyxia
- Some postnatal = meningitis, abuse
4
Q
ASD criteria
A
- Social communication (reciprocity, nonverbals, relationships)
- Restrictive and repetitive behaviors (fixed interests, stereotypy, rigidity, sensitivity)
- Onset = early developmental period
5
Q
ASD best prognosis
A
- IQ > 70
- Language by 5yo
- No comorbidities
6
Q
ASD and brain structure
A
- Accelerated brain growth
- Structures affected = cerebellum, corpus callosum, amygdala
7
Q
ASD and NTs
A
Lower:
1. Brain serotonin
2. GABA
Higher:
1. Blood serotonin
2. Glutamate
3. Acetylcholine
8
Q
ASD prevalence
A
1-2%
3-4x in males
9
Q
ASD heritability
A
Monozygotic = 69-95%
Dizygotic = 0-24%
10
Q
ASD treatment
A
- ABA (affects IQ and language)
- Medication for comorbidities
11
Q
ADHD criteria
A
- Duration > 6 months
- Onset < 12yo
- 2+ settings
- 6+ symptoms (5+ for adults)
12
Q
ADHD prevalence
A
- Most prevalent dx in 3-17 yo
- 2x more in males
13
Q
ADHD heritability
A
One of the most heritable disorders
- All twins = 76%
- Monozygotic = 71%
- Dizygotic = 41%
14
Q
ADHD risk factors
A
- Low birth weight
- Premature birth
- Maternal tobacco/alcohol use
15
Q
ADHD comorbidities
A
- ODD*
- CD
- Anxiety
- Depression
- Adulthood SUDs (not due to meds)