Neurodegenerative Diseases Flashcards

1
Q

how to DC DMARDs with MLF

A

you must employ MLF for at least 12 months with good
effect before even attempting to gradually transition to less potent
immune suppressive drug therapy.

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2
Q

Melatonin and AD

A

Improves sleep,
decreases sundowning
slows prog of cognitive impairment
dec beta amyloid

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3
Q

light exposure and neurodeg

A

•↓ morning light exposure is associated with poorer sleep

quality

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4
Q

IL-10 and exercise

A

exercise x 6 mo improves IL 10 and sleep

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5
Q

MS and food triggers

A

linked to dairy intake (milk)

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6
Q

food triggers and SCZ

A

higher IgG food sens to gluten and casein

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7
Q

Mushrooms effects

A

Activate NK cells
Prime immune system
dec cog decline
dec depression

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8
Q

Vit K found in

A

greens

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9
Q

Vit K2 effects

A

Ca into bones/teeth

neural stem cells and myelin production

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10
Q

MCT based keto diet

A

can have more carbs than olive oil (60-80kcal/day) but check fasting lipids!

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11
Q

smoking and neurodeg

A

higher risk

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12
Q

statins and neurodeg

A

block remyelination

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13
Q

DM + ApoE4 and AD

A

synergistic (5x increase)

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14
Q

How to increase BDNF in neurodegenerative pts?

A

exercise
mushrooms
fasting/ketosis/ metabolic switching.

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15
Q

TBI and neurodeg

A

increases risk of all!

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16
Q

CDP Choline effect

can also get with

A

can rebuild myelin
dose: CPD Choline 500 mg to 1 g bid
Or PC 1 4 tbsp day as liposomes
can use with upstream phosaphidyl choline

17
Q

9 cup veggie breakdown

A

3 green, 3 colored, 3 sulfur