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Psychiatry > Neurochemistry of Memory > Flashcards

Neurochemistry of Memory Flashcards

1
Q

This part of the brain is responsible for emotional responses

A

Amygdala

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2
Q

Part of the brain involved in declarartive (explicit) memory

A

Hippocampus
Medial temporal lobe
Diencephalon

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3
Q

Affects mood, hunger, sleep and arousal

A

Serotonin

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4
Q

Influences movement, learning, attention and emotional

A

Dopamine

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5
Q

Undersupply linked to depression

A

Serotonin

Noradrenaline

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6
Q

Oversupply linked to schizophrenia

A

Dopamine

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7
Q

Undersupply linked to tremors and decreased mobility in Parkinsons

A

Dopamine

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8
Q

Undersupply linked to ADHD

A

Dopamine

Noradrenaline

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9
Q

Neurotransmitter that enables muscle action, learning and memory

A

Acetylcholine

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10
Q

Which neurones deteriorate as Alzheimer’s disease progresses?

A

ACh-producing neurones

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11
Q

Helps control alertness and arousal

A

NA

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12
Q

Undersupply can depress mood and cause ADHD-like problems

A

NA

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13
Q

Undersupply linked to seizures, tremors and insomnia

A

GABA (bc its inhibitory so not enough = your body is super excited)

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14
Q

Oversupply can stimulate the brain producing migraines or seizures

A

Glutamate (why some people avoid MSG foods haha)

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15
Q

Most frequent neurotransmitter in the CNS

A

Glutamate

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16
Q

Which channels does ACh work on and how?

A

Inhibits nicotinic ion channels by depolarisation

17
Q

Key role in memory, attention and arousal

A

ACh

18
Q

Which receptors does glutamate work on?

A

AMPA
Metabotropic
NMDA

19
Q

This is involved in post-synaptic long term potentiation

A

Glutamate

20
Q

These receptors produce rapid responses to glutamate

A

AMPA

21
Q

These receptors are responsible for synaptic plasticity and are key in long term potentiation
-how do they work?

A

NMDA
-allow Calcium influx

(glutamate responsible for this)
(AMPA also play a role)

22
Q

Agonists reduce or prevent neuro inflammation and modualte mitochondrial function

A

PPARy

23
Q

Role of ApoE

A

Cholesterol metabolism
Membrane stability and repair

-problems with this gene in alzheimers

24
Q

Role of tau protein

A

Stabilises microtubules

25
Q

Purpose of striatal interneurones

A

Motor control

26
Q

Purpose of the nucelus basalis of Meynert?

A

Attention/arousal

27
Q

Purpose of medial septal nucleus?

A

Learning and memory

28
Q

Alzheimers meds/ drugs which prevent ACh breakdown?

A

Galantamine
Rivestigmine
Donepezil

Psychiatry (29 decks)

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